CC020_MOUSE
ID CC020_MOUSE Reviewed; 933 AA.
AC Q8CDN1;
DT 21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Uncharacterized protein C3orf20 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AK029822; BAC26632.1; -; mRNA.
DR CCDS; CCDS51853.1; -.
DR RefSeq; NP_941070.1; NM_198668.2.
DR RefSeq; XP_006506395.1; XM_006506332.3.
DR AlphaFoldDB; Q8CDN1; -.
DR STRING; 10090.ENSMUSP00000053778; -.
DR PhosphoSitePlus; Q8CDN1; -.
DR jPOST; Q8CDN1; -.
DR MaxQB; Q8CDN1; -.
DR PaxDb; Q8CDN1; -.
DR PeptideAtlas; Q8CDN1; -.
DR PRIDE; Q8CDN1; -.
DR Antibodypedia; 45080; 69 antibodies from 15 providers.
DR Ensembl; ENSMUST00000059318; ENSMUSP00000053778; ENSMUSG00000034063.
DR Ensembl; ENSMUST00000205686; ENSMUSP00000146101; ENSMUSG00000034063.
DR GeneID; 381798; -.
DR KEGG; mmu:381798; -.
DR UCSC; uc009cyl.1; mouse.
DR MGI; MGI:2685917; 4930590J08Rik.
DR VEuPathDB; HostDB:ENSMUSG00000034063; -.
DR eggNOG; KOG4106; Eukaryota.
DR GeneTree; ENSGT00940000153655; -.
DR HOGENOM; CLU_015383_0_0_1; -.
DR InParanoid; Q8CDN1; -.
DR OMA; QEMCRHI; -.
DR OrthoDB; 222632at2759; -.
DR PhylomeDB; Q8CDN1; -.
DR TreeFam; TF333451; -.
DR BioGRID-ORCS; 381798; 3 hits in 73 CRISPR screens.
DR PRO; PR:Q8CDN1; -.
DR Proteomes; UP000000589; Chromosome 6.
DR RNAct; Q8CDN1; protein.
DR Bgee; ENSMUSG00000034063; Expressed in testis and 46 other tissues.
DR ExpressionAtlas; Q8CDN1; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; ISO:MGI.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR029281; FAM194_C.
DR Pfam; PF14977; FAM194; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..933
FT /note="Uncharacterized protein C3orf20 homolog"
FT /id="PRO_0000228844"
FT TRANSMEM 771..791
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 244..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 890..933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 933 AA; 104228 MW; 4EC41A7D9953321E CRC64;
MNQIKSNREL YLQYSASAPK LLAHVSKLLI FCRNSGISIP KGIRNIFEFT WEELINDPAV
PTASEIQDLV VTFGTPTVVL AEVIPVQVLP MQKKQPPPAP PPTLMPAATS GGKYVPPTST
SAKLMPNGQN TLHKFQRQSI HLLTELLSLK MKAMVESASA GANPLDITKR FVEASQLLHL
NAKEMAFDCL TGTVGKSCLS TAQLGKESSM NISAMGVNTP YQLVYQTSTA CLSFSLCTGK
ESRKKDIGAK PKPVDDVSPQ PVRARTPPEN TVVELPDPCP EAREKLQDMC RHIEAERILW
RGRNASCPMI FRNYRSRISS HLMLASKGDS HHPLTTGTQI TASAPHQPSS QHAQMGRHSQ
EWKGPKKPIK LHYTFYDGSS FIYYPSGNIA LLQIPTCCRG KPITCLFNDM PNTFLALFNA
EGLGCVYYNL KNCCPYVLVL DEEGGITNDQ KGYIVHRWSW ASKTETLLSL EYKVNEQMKL
TVLGQDSITV TFTSMNETVT ISVSPKSCPH NVLHDKRPVR RISLMDEKVS KTNRALAEIK
KRFQKTVTQF MNSVLLAAGL FTLEYPNPKE TETSRVKLKP GSNQDRIRKT SLYQGENHMR
IQSARQDSII NETLKEDSIL TSLAHVQKKN GKVQVKVLPR GKRREVRSPT RWAASPSDCP
LVLRRLILKE DIRAGCKCIV KAPLVSDLEL ERFLSAPRDP NQVLVFGIMS SQDPTLTAQL
QWLMDTLYSH LQQGRSSPCI QCRHDPYRLL RYDLDSPLQK DPPLMVKKFA VIHGMVLMFA
GGKLLFGGCV LNGYGFSKQN LLKQIFRAQQ DCKMGYFLPD NYKFKHDAFK ASRIAKPCGL
SSRGVPSQFL GLETEPSMST YVTNLDDTES TKKPPSDDYE GSVSSVALVD KIEKEPPPSP
EKVKPPEIEL QPFTKMRRSS KKTAGFKKLN SKK
