ID   YUPP_METHO              Reviewed;         282 AA.
AC   P43051;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Putative phosphatase in upp 3'region;
DE            EC=3.1.3.-;
OS   Metamycoplasma hominis (Mycoplasma hominis).
OC   Bacteria; Tenericutes; Mycoplasmoidales; Metamycoplasmataceae;
OC   Metamycoplasma.
OX   NCBI_TaxID=2098;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FBG;
RA   Schuchart K.;
RL   Thesis (1993), Heinrich-Heine University / Duesseldorf, Germany.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily. Cof family.
CC       {ECO:0000305}.
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DR   EMBL; Z27121; CAA81648.1; -; Genomic_DNA.
DR   AlphaFoldDB; P43051; -.
DR   SMR; P43051; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016791; F:phosphatase activity; IEA:UniProt.
DR   Gene3D; 3.40.50.1000; -; 1.
DR   InterPro; IPR000150; Cof.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006379; HAD-SF_hydro_IIB.
DR   InterPro; IPR023214; HAD_sf.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   TIGRFAMs; TIGR00099; Cof-subfamily; 1.
DR   TIGRFAMs; TIGR01484; HAD-SF-IIB; 1.
DR   PROSITE; PS01228; COF_1; 1.
DR   PROSITE; PS01229; COF_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Metal-binding.
FT   CHAIN           1..282
FT                   /note="Putative phosphatase in upp 3'region"
FT                   /id="PRO_0000054443"
FT   ACT_SITE        17
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000250"
FT   BINDING         17
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         18
FT                   /ligand="phosphate"
FT                   /ligand_id="ChEBI:CHEBI:43474"
FT                   /evidence="ECO:0000250"
FT   BINDING         19
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         53..54
FT                   /ligand="phosphate"
FT                   /ligand_id="ChEBI:CHEBI:43474"
FT                   /evidence="ECO:0000250"
FT   BINDING         211
FT                   /ligand="phosphate"
FT                   /ligand_id="ChEBI:CHEBI:43474"
FT                   /evidence="ECO:0000250"
FT   BINDING         234
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         235
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         237
FT                   /ligand="phosphate"
FT                   /ligand_id="ChEBI:CHEBI:43474"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   282 AA;  31582 MW;  660C86388EFE11C6 CRC64;
     MAYNKESKQR RFLFAIDLDG TLLADSANGT VHPKTEEAIK KAVAQGHIVS IITGRPWRST
     LPVYEKLGLN AIVGNYNGAH IHNPADPFFI PAITYLDLNE VLYILGDEKV KKEITNYAIE
     GPDWVQLMHR DPNLERVFGF NQATKFRECI NLEKIPLKPT GIVFDVKPDT DVLELLTYLK
     RRYGDLGEFS SWSKGEGLSP VFDITSIGID KGKVISLIMR YYNIDIDDTV AMGDSYNDLS
     MYNVANVCVS PANAEPLIKK MSTVVMKQTN KEGAVGYFID HS