YURK_BACSU
ID YURK_BACSU Reviewed; 242 AA.
AC O32152;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator YurK;
GN Name=yurK; OrderedLocusNames=BSU32560;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
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DR EMBL; AL009126; CAB15246.1; -; Genomic_DNA.
DR PIR; B70018; B70018.
DR RefSeq; NP_391136.2; NC_000964.3.
DR RefSeq; WP_003228628.1; NZ_JNCM01000033.1.
DR PDB; 2IKK; X-ray; 1.80 A; A/B=94-242.
DR PDBsum; 2IKK; -.
DR AlphaFoldDB; O32152; -.
DR SMR; O32152; -.
DR STRING; 224308.BSU32560; -.
DR PaxDb; O32152; -.
DR PRIDE; O32152; -.
DR DNASU; 936688; -.
DR EnsemblBacteria; CAB15246; CAB15246; BSU_32560.
DR GeneID; 936688; -.
DR KEGG; bsu:BSU32560; -.
DR PATRIC; fig|224308.179.peg.3526; -.
DR eggNOG; COG2188; Bacteria.
DR InParanoid; O32152; -.
DR OMA; QVVPTHN; -.
DR BioCyc; BSUB:BSU32560-MON; -.
DR EvolutionaryTrace; O32152; -.
DR PRO; PR:O32152; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 3.40.1410.10; -; 1.
DR InterPro; IPR028978; Chorismate_lyase_/UTRA_dom_sf.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR011663; UTRA.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00392; GntR; 1.
DR Pfam; PF07702; UTRA; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SMART; SM00866; UTRA; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR SUPFAM; SSF64288; SSF64288; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..242
FT /note="Uncharacterized HTH-type transcriptional regulator
FT YurK"
FT /id="PRO_0000050691"
FT DOMAIN 8..76
FT /note="HTH gntR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT DNA_BIND 36..55
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT STRAND 102..110
FT /evidence="ECO:0007829|PDB:2IKK"
FT HELIX 113..119
FT /evidence="ECO:0007829|PDB:2IKK"
FT STRAND 126..149
FT /evidence="ECO:0007829|PDB:2IKK"
FT TURN 150..152
FT /evidence="ECO:0007829|PDB:2IKK"
FT HELIX 156..159
FT /evidence="ECO:0007829|PDB:2IKK"
FT HELIX 166..174
FT /evidence="ECO:0007829|PDB:2IKK"
FT STRAND 180..189
FT /evidence="ECO:0007829|PDB:2IKK"
FT HELIX 192..198
FT /evidence="ECO:0007829|PDB:2IKK"
FT STRAND 205..215
FT /evidence="ECO:0007829|PDB:2IKK"
FT HELIX 216..218
FT /evidence="ECO:0007829|PDB:2IKK"
FT STRAND 219..229
FT /evidence="ECO:0007829|PDB:2IKK"
FT TURN 230..232
FT /evidence="ECO:0007829|PDB:2IKK"
FT STRAND 233..237
FT /evidence="ECO:0007829|PDB:2IKK"
SQ SEQUENCE 242 AA; 27510 MW; 0CD47CCAF9E9F9A0 CRC64;
MLNNGSSTPL YIQLKQIITD DIKKGVYSPT AKLPTENELC TKYNVSRITV RKAILDLVEE
GYLIRQQGKG TFVKSPKLKR ELIAVNGYSE FMESTGKKPK HHVLSHDIIP ASKPIAEKLQ
IQPESPVVEL KRILYNDDQP LTFEVTHYPL DLFPGIDTFI ADGVSMHDIL KQQYKVVPTH
NTKLLNVVYA QQEESKYLDC DIGDALFEID KTAFTSNDQP IYCSLFLMHT NRVTFTINSP
YT
