ID   YUSO_BACSU              Reviewed;         155 AA.
AC   O32181;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YusO;
GN   Name=yusO; OrderedLocusNames=BSU32870;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL009126; CAB15276.1; -; Genomic_DNA.
DR   PIR; H70021; H70021.
DR   RefSeq; NP_391166.1; NC_000964.3.
DR   RefSeq; WP_003242592.1; NZ_JNCM01000033.1.
DR   PDB; 1S3J; X-ray; 2.25 A; A/B=1-155.
DR   PDBsum; 1S3J; -.
DR   AlphaFoldDB; O32181; -.
DR   SMR; O32181; -.
DR   STRING; 224308.BSU32870; -.
DR   PaxDb; O32181; -.
DR   PRIDE; O32181; -.
DR   EnsemblBacteria; CAB15276; CAB15276; BSU_32870.
DR   GeneID; 935923; -.
DR   KEGG; bsu:BSU32870; -.
DR   PATRIC; fig|224308.179.peg.3563; -.
DR   eggNOG; COG1846; Bacteria.
DR   InParanoid; O32181; -.
DR   OMA; EHFITRY; -.
DR   PhylomeDB; O32181; -.
DR   BioCyc; BSUB:BSU32870-MON; -.
DR   EvolutionaryTrace; O32181; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01047; MarR; 1.
DR   PRINTS; PR00598; HTHMARR.
DR   SMART; SM00347; HTH_MARR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50995; HTH_MARR_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..155
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YusO"
FT                   /id="PRO_0000360555"
FT   DOMAIN          4..140
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
FT   DNA_BIND        54..77
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
FT   HELIX           4..32
FT                   /evidence="ECO:0007829|PDB:1S3J"
FT   HELIX           37..49
FT                   /evidence="ECO:0007829|PDB:1S3J"
FT   STRAND          50..53
FT                   /evidence="ECO:0007829|PDB:1S3J"
FT   HELIX           54..61
FT                   /evidence="ECO:0007829|PDB:1S3J"
FT   HELIX           65..77
FT                   /evidence="ECO:0007829|PDB:1S3J"
FT   STRAND          80..85
FT                   /evidence="ECO:0007829|PDB:1S3J"
FT   STRAND          92..97
FT                   /evidence="ECO:0007829|PDB:1S3J"
FT   HELIX           99..120
FT                   /evidence="ECO:0007829|PDB:1S3J"
FT   HELIX           125..143
FT                   /evidence="ECO:0007829|PDB:1S3J"
SQ   SEQUENCE   155 AA;  17400 MW;  21B31E4B1E4ED0BD CRC64;
     MKSADQLMSD IQLSLQALFQ KIQPEMLESM EKQGVTPAQL FVLASLKKHG SLKVSEIAER
     MEVKPSAVTL MADRLEQKNL IARTHNTKDR RVIDLSLTDE GDIKFEEVLA GRKAIMARYL
     SFLTEEEMLQ AAHITAKLAQ AAETDEKQNM KRGNG