CC036_HUMAN
ID CC036_HUMAN Reviewed; 165 AA.
AC Q3SXR2; Q3SXR3; Q9H6K8;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Uncharacterized protein C3orf36;
GN Name=C3orf36;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q3SXR2; Q49AR9: ANKS1A; NbExp=3; IntAct=EBI-18036948, EBI-11954519;
CC Q3SXR2; Q8N9N5-2: BANP; NbExp=3; IntAct=EBI-18036948, EBI-11524452;
CC Q3SXR2; P55212: CASP6; NbExp=3; IntAct=EBI-18036948, EBI-718729;
CC Q3SXR2; Q8NI60: COQ8A; NbExp=3; IntAct=EBI-18036948, EBI-745535;
CC Q3SXR2; P99999: CYCS; NbExp=3; IntAct=EBI-18036948, EBI-446479;
CC Q3SXR2; P22607: FGFR3; NbExp=3; IntAct=EBI-18036948, EBI-348399;
CC Q3SXR2; Q14957: GRIN2C; NbExp=3; IntAct=EBI-18036948, EBI-8285963;
CC Q3SXR2; P06396: GSN; NbExp=3; IntAct=EBI-18036948, EBI-351506;
CC Q3SXR2; Q8WUI4-6: HDAC7; NbExp=3; IntAct=EBI-18036948, EBI-12094670;
CC Q3SXR2; O14964: HGS; NbExp=3; IntAct=EBI-18036948, EBI-740220;
CC Q3SXR2; O00291: HIP1; NbExp=3; IntAct=EBI-18036948, EBI-473886;
CC Q3SXR2; P30519: HMOX2; NbExp=3; IntAct=EBI-18036948, EBI-712096;
CC Q3SXR2; P13473-2: LAMP2; NbExp=3; IntAct=EBI-18036948, EBI-21591415;
CC Q3SXR2; Q13163: MAP2K5; NbExp=3; IntAct=EBI-18036948, EBI-307294;
CC Q3SXR2; Q16656-4: NRF1; NbExp=3; IntAct=EBI-18036948, EBI-11742836;
CC Q3SXR2; Q92569: PIK3R3; NbExp=3; IntAct=EBI-18036948, EBI-79893;
CC Q3SXR2; Q13526: PIN1; NbExp=3; IntAct=EBI-18036948, EBI-714158;
CC Q3SXR2; Q96I34: PPP1R16A; NbExp=3; IntAct=EBI-18036948, EBI-710402;
CC Q3SXR2; P67775: PPP2CA; NbExp=3; IntAct=EBI-18036948, EBI-712311;
CC Q3SXR2; O43741: PRKAB2; NbExp=3; IntAct=EBI-18036948, EBI-1053424;
CC Q3SXR2; O75400-2: PRPF40A; NbExp=3; IntAct=EBI-18036948, EBI-5280197;
CC Q3SXR2; P86480: PRR20D; NbExp=3; IntAct=EBI-18036948, EBI-12754095;
CC Q3SXR2; P62826: RAN; NbExp=3; IntAct=EBI-18036948, EBI-286642;
CC Q3SXR2; Q5TAB7: RIPPLY2; NbExp=3; IntAct=EBI-18036948, EBI-10246897;
CC Q3SXR2; P31948: STIP1; NbExp=3; IntAct=EBI-18036948, EBI-1054052;
CC Q3SXR2; Q96A09: TENT5B; NbExp=3; IntAct=EBI-18036948, EBI-752030;
CC Q3SXR2; Q9UMX0: UBQLN1; NbExp=3; IntAct=EBI-18036948, EBI-741480;
CC Q3SXR2; P0CB47: UBTFL1; NbExp=3; IntAct=EBI-18036948, EBI-17208936;
CC Q3SXR2; P36508: ZNF76; NbExp=3; IntAct=EBI-18036948, EBI-7254550;
CC Q3SXR2; Q9Y649; NbExp=3; IntAct=EBI-18036948, EBI-25900580;
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DR EMBL; AK025826; BAB15249.1; -; mRNA.
DR EMBL; BC104161; AAI04162.1; -; mRNA.
DR EMBL; BC104162; AAI04163.1; -; mRNA.
DR RefSeq; NP_079317.2; NM_025041.2.
DR AlphaFoldDB; Q3SXR2; -.
DR BioGRID; 123117; 26.
DR IntAct; Q3SXR2; 32.
DR STRING; 9606.ENSP00000386219; -.
DR BioMuta; C3orf36; -.
DR DMDM; 115503730; -.
DR PaxDb; Q3SXR2; -.
DR PRIDE; Q3SXR2; -.
DR UCSC; uc003epz.2; human.
DR GeneCards; C3orf36; -.
DR HGNC; HGNC:26170; C3orf36.
DR neXtProt; NX_Q3SXR2; -.
DR PharmGKB; PA142672397; -.
DR eggNOG; ENOG502THCB; Eukaryota.
DR HOGENOM; CLU_1829885_0_0_1; -.
DR OrthoDB; 1254345at2759; -.
DR PathwayCommons; Q3SXR2; -.
DR SignaLink; Q3SXR2; -.
DR BioGRID-ORCS; 80111; 13 hits in 979 CRISPR screens.
DR GenomeRNAi; 80111; -.
DR Pharos; Q3SXR2; Tdark.
DR PRO; PR:Q3SXR2; -.
DR Proteomes; UP000005640; Chromosome 3.
DR RNAct; Q3SXR2; protein.
DR Genevisible; Q3SXR2; HS.
DR InterPro; IPR040620; DUF5560.
DR Pfam; PF17715; DUF5560; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..165
FT /note="Uncharacterized protein C3orf36"
FT /id="PRO_0000251963"
FT REGION 68..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..107
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 57
FT /note="F -> L (in Ref. 2; AAI04162)"
FT /evidence="ECO:0000305"
FT CONFLICT 78
FT /note="H -> R (in Ref. 1; BAB15249)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 165 AA; 16908 MW; 5DCECBA09490CD24 CRC64;
MQAETILEGL EAGLPQAVSS GLSLVPAPGL VLTCLSAPSG PGGMALEPPP TTLRKAFLAQ
STLLESTLEG APEWAAPHPE EQRRSPPACS QHTPPLPSTP TGPPPCSPGG NHPLCALSGR
GGGRCSIPSL SSSSTFSLFS SGCWNPRVKL RVRKSQSQGR AGQLI
