ID   YUTD_BACSU              Reviewed;          91 AA.
AC   O32127;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 2.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Putative antitoxin YutD {ECO:0000305};
GN   Name=yutD; OrderedLocusNames=BSU32310;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   STRUCTURE BY NMR, AND DISULFIDE BOND.
RG   Northeast structural genomics consortium (NESG);
RT   "Solution NMR structure of protein yutD from B.subtilis, Northeast
RT   structural genomics consortium target sr232.";
RL   Submitted (JUL-2009) to the PDB data bank.
CC   -!- FUNCTION: Probable antitoxin component of a putative type VII toxin-
CC       antitoxin (TA) system. Probably neutralizes cognate toxin YutE.
CC       {ECO:0000305}.
CC   -!- SUBUNIT: Homodimer, probably forms a complex with cognate toxin YutE.
CC       {ECO:0000305}.
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DR   EMBL; AL009126; CAB15221.2; -; Genomic_DNA.
DR   RefSeq; NP_391111.2; NC_000964.3.
DR   RefSeq; WP_003228682.1; NZ_JNCM01000033.1.
DR   PDB; 2KL5; NMR; -; A=1-91.
DR   PDBsum; 2KL5; -.
DR   AlphaFoldDB; O32127; -.
DR   BMRB; O32127; -.
DR   SMR; O32127; -.
DR   STRING; 224308.BSU32310; -.
DR   PaxDb; O32127; -.
DR   PRIDE; O32127; -.
DR   DNASU; 937182; -.
DR   EnsemblBacteria; CAB15221; CAB15221; BSU_32310.
DR   GeneID; 50136232; -.
DR   GeneID; 937182; -.
DR   KEGG; bsu:BSU32310; -.
DR   PATRIC; fig|224308.179.peg.3498; -.
DR   eggNOG; COG4470; Bacteria.
DR   OMA; FDDHNQK; -.
DR   PhylomeDB; O32127; -.
DR   BioCyc; BSUB:BSU32310-MON; -.
DR   EvolutionaryTrace; O32127; -.
DR   PRO; PR:O32127; -.
DR   Proteomes; UP000001570; Chromosome.
DR   Gene3D; 3.50.4.20; -; 1.
DR   InterPro; IPR009370; YutD-like.
DR   InterPro; IPR038141; YutD-like_sf.
DR   Pfam; PF06265; DUF1027; 1.
DR   PIRSF; PIRSF012565; DUF1027; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Disulfide bond; Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..91
FT                   /note="Putative antitoxin YutD"
FT                   /id="PRO_0000388969"
FT   DISULFID        77..81
FT                   /evidence="ECO:0000269|Ref.2"
FT   STRAND          1..4
FT                   /evidence="ECO:0007829|PDB:2KL5"
FT   STRAND          7..15
FT                   /evidence="ECO:0007829|PDB:2KL5"
FT   HELIX           21..27
FT                   /evidence="ECO:0007829|PDB:2KL5"
FT   HELIX           30..34
FT                   /evidence="ECO:0007829|PDB:2KL5"
FT   STRAND          36..41
FT                   /evidence="ECO:0007829|PDB:2KL5"
FT   STRAND          48..51
FT                   /evidence="ECO:0007829|PDB:2KL5"
FT   HELIX           69..75
FT                   /evidence="ECO:0007829|PDB:2KL5"
FT   STRAND          83..88
FT                   /evidence="ECO:0007829|PDB:2KL5"
SQ   SEQUENCE   91 AA;  10922 MW;  54BECBA2F573E8D2 CRC64;
     MILIQNAEFE LVHNFKDGFN EEAFKARYSD ILNKYDYIVG DWGYGQLRLK GFFDDQNQKA
     TFETKISTLD EYIYEYCNFG CAYFVLKRIR K