YUTE_BACSU
ID YUTE_BACSU Reviewed; 144 AA.
AC O32126;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Putative RNase YutE {ECO:0000250|UniProtKB:Q8ECH6};
DE EC=3.1.-.- {ECO:0000250|UniProtKB:Q8ECH6};
DE AltName: Full=Putative toxin HepT {ECO:0000305};
GN Name=yutE; Synonyms=hepT {ECO:0000250|UniProtKB:Q8ECH6};
GN OrderedLocusNames=BSU32300;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (1.83 ANGSTROMS).
RG Midwest center for structural genomics (MCSG);
RT "Hypothetical cytosolic protein yutE from Bacillus subtilis.";
RL Submitted (MAR-2005) to the PDB data bank.
CC -!- FUNCTION: Probable toxic component of a putative type VII toxin-
CC antitoxin (TA) system, probably an RNase. Probably neutralized by
CC cognate antitoxin YutD. {ECO:0000305}.
CC -!- SUBUNIT: Homodimer, probably forms a complex with cognate antitoxin
CC YutD. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the HepT RNase toxin family. {ECO:0000305}.
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DR EMBL; AL009126; CAB15220.1; -; Genomic_DNA.
DR PIR; G70023; G70023.
DR RefSeq; NP_391110.1; NC_000964.3.
DR RefSeq; WP_003228684.1; NZ_CP053102.1.
DR PDB; 1YLM; X-ray; 1.83 A; A/B=1-144.
DR PDBsum; 1YLM; -.
DR AlphaFoldDB; O32126; -.
DR SMR; O32126; -.
DR STRING; 224308.BSU32300; -.
DR PaxDb; O32126; -.
DR PRIDE; O32126; -.
DR EnsemblBacteria; CAB15220; CAB15220; BSU_32300.
DR GeneID; 938483; -.
DR KEGG; bsu:BSU32300; -.
DR PATRIC; fig|224308.179.peg.3497; -.
DR eggNOG; COG2445; Bacteria.
DR InParanoid; O32126; -.
DR OMA; MYFVDRE; -.
DR PhylomeDB; O32126; -.
DR BioCyc; BSUB:BSU32300-MON; -.
DR EvolutionaryTrace; O32126; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0110001; C:toxin-antitoxin complex; IEA:InterPro.
DR GO; GO:0004540; F:ribonuclease activity; IEA:InterPro.
DR Gene3D; 1.20.120.580; -; 1.
DR InterPro; IPR008201; HepT-like.
DR InterPro; IPR037038; HepT-like_sf.
DR Pfam; PF01934; DUF86; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Hydrolase; Nuclease; Reference proteome;
KW Toxin-antitoxin system.
FT CHAIN 1..144
FT /note="Putative RNase YutE"
FT /id="PRO_0000359923"
FT MOTIF 96..103
FT /note="RX(4)HXY motif"
FT /evidence="ECO:0000250|UniProtKB:A0A0B0QJR1"
FT ACT_SITE 96
FT /evidence="ECO:0000250|UniProtKB:A0A0B0QJR1"
FT HELIX 6..23
FT /evidence="ECO:0007829|PDB:1YLM"
FT STRAND 29..31
FT /evidence="ECO:0007829|PDB:1YLM"
FT HELIX 32..59
FT /evidence="ECO:0007829|PDB:1YLM"
FT HELIX 68..70
FT /evidence="ECO:0007829|PDB:1YLM"
FT HELIX 71..77
FT /evidence="ECO:0007829|PDB:1YLM"
FT HELIX 83..93
FT /evidence="ECO:0007829|PDB:1YLM"
FT HELIX 96..100
FT /evidence="ECO:0007829|PDB:1YLM"
FT HELIX 103..105
FT /evidence="ECO:0007829|PDB:1YLM"
FT HELIX 108..117
FT /evidence="ECO:0007829|PDB:1YLM"
FT HELIX 119..137
FT /evidence="ECO:0007829|PDB:1YLM"
FT TURN 138..140
FT /evidence="ECO:0007829|PDB:1YLM"
SQ SEQUENCE 144 AA; 16650 MW; C89177BB90B3685D CRC64;
MYFVDRSKIE KTLGFFEHQL ALFDSQTDWQ SEIGELALQR IGHLLIECIL DTGNDMIDGF
IMRDPGSYDD IMDILVDEKV VTEKEGDELK KLIAYRKTLV QQYLLADSGE LYRLIKAHQT
ALQDFPKRIR SYLETELGPV SAFK
