ID   YUXG_BACSU              Reviewed;         689 AA.
AC   P40747;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 2.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Uncharacterized oxidoreductase YuxG;
DE            EC=1.-.-.-;
DE   AltName: Full=ORF2;
GN   Name=yuxG; Synonyms=yulA; OrderedLocusNames=BSU31220;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9274030; DOI=10.1099/00221287-143-8-2769;
RA   Oudega B., Koningstein G., Rodrigues L., de Sales Ramon M., Hilbert H.,
RA   Duesterhoeft A., Pohl T.M., Weitzenegger T.;
RT   "Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence
RT   of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai).";
RL   Microbiology 143:2769-2774(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-49.
RC   STRAIN=168 / OI1085;
RX   PubMed=8188684; DOI=10.1016/s0021-9258(17)36752-2;
RA   Hanlon D.W., Ordal G.W.;
RT   "Cloning and characterization of genes encoding methyl-accepting chemotaxis
RT   proteins in Bacillus subtilis.";
RL   J. Biol. Chem. 269:14038-14046(1994).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; Z93938; CAB07952.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15100.1; -; Genomic_DNA.
DR   EMBL; L29189; AAA20558.2; -; Genomic_DNA.
DR   PIR; H70024; H70024.
DR   RefSeq; NP_391000.1; NC_000964.3.
DR   RefSeq; WP_003244479.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; P40747; -.
DR   SMR; P40747; -.
DR   STRING; 224308.BSU31220; -.
DR   PaxDb; P40747; -.
DR   PRIDE; P40747; -.
DR   DNASU; 938841; -.
DR   EnsemblBacteria; CAB15100; CAB15100; BSU_31220.
DR   GeneID; 938841; -.
DR   KEGG; bsu:BSU31220; -.
DR   PATRIC; fig|224308.179.peg.3382; -.
DR   eggNOG; COG1028; Bacteria.
DR   eggNOG; COG3347; Bacteria.
DR   InParanoid; P40747; -.
DR   OMA; KHGLVTW; -.
DR   PhylomeDB; P40747; -.
DR   BioCyc; BSUB:BSU31220-MON; -.
DR   BioCyc; MetaCyc:BSU31220-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.225.10; -; 1.
DR   InterPro; IPR001303; Aldolase_II/adducin_N.
DR   InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR   InterPro; IPR013454; Bifunc_RhaD/ADH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00596; Aldolase_II; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SMART; SM01007; Aldolase_II; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF53639; SSF53639; 1.
DR   TIGRFAMs; TIGR02632; RhaD_aldol-ADH; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..689
FT                   /note="Uncharacterized oxidoreductase YuxG"
FT                   /id="PRO_0000054850"
FT   ACT_SITE        579
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         566
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   689 AA;  76020 MW;  88A82FDC3EEDD0FD CRC64;
     MVKHIWDSER AAQLPKGVEE LVYRSNLIGS DRTVCNWGGG NTSMKTTEKD FRGREIEVMW
     VKGSGSDLAT MKAHNFSGLK LDDIRPLIKR DQMPDEEMVD YLSHCMIDSK HPRPSIETLL
     HAFLPYKHVD HTHPDAIISI CCADNGKQIA EDIYGNRFVW VPYVRPGFTL SKMIAEGVAN
     NPHAELVLME KHGLVTWGET SETCYQKTIS IIQEAEQYIN DRINQHEVFG GKRYQPLPED
     KRKQILAGIM PVIRGAVSEE KKMILSYDDH DDVLEFVNSV QAPALSQIGA ACPDHLVHTK
     RVPLYIDWNP ETQDVHKLAD LIKSGVETFT SEYQAYFTRN QQDGDQIFES APRVILIPGI
     GMVNTGKSYA MSKVSGALYR RAIAVMKGAT ALGQFVSLHE NESYHVEYWP LELYKLTLAP
     PEAEFSRKVA LITGGAGGIG SAACRRFAAE GGHVIVADLN IEGAQKIAGE INDAYGKGRA
     MAVKMDVTKE EDVQSAFERA ALAYGGIDIV VNNAGLATSS PFDETSLKEW NLNMNVLGTG
     YFLVAREAFK QMKHQNRGGS MVFVGSKNSV YAGKNASAYS SVKALETHLA RCIAAEGGEF
     GIRVNSVLPD AVLQGSAIWG SSWREERAAA YGIEPDQLEE HYRKRTALLV NIYPEDIAEA
     IAFFASSKAE KTTGCMITVD GGVPAAFTR