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YUXH_BACSU
ID   YUXH_BACSU              Reviewed;         409 AA.
AC   P14203;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Uncharacterized protein YuxH;
GN   Name=yuxH; Synonyms=yufA; OrderedLocusNames=BSU31740;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2507523; DOI=10.1128/jb.171.10.5362-5375.1989;
RA   Weinrauch Y., Guillen N., Dubnau D.;
RT   "Sequence and transcription mapping of Bacillus subtilis competence genes
RT   comB and comA, one of which is related to a family of bacterial regulatory
RT   determinants.";
RL   J. Bacteriol. 171:5362-5375(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9274030; DOI=10.1099/00221287-143-8-2769;
RA   Oudega B., Koningstein G., Rodrigues L., de Sales Ramon M., Hilbert H.,
RA   Duesterhoeft A., Pohl T.M., Weitzenegger T.;
RT   "Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence
RT   of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai).";
RL   Microbiology 143:2769-2774(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [4]
RP   SHOWS THAT THIS IS NOT COMB.
RX   PubMed=1943994; DOI=10.1128/mr.55.3.395-424.1991;
RA   Dubnau D.;
RT   "Genetic competence in Bacillus subtilis.";
RL   Microbiol. Rev. 55:395-424(1991).
CC   -!- CAUTION: Was originally thought to be comB, a competence gene.
CC       {ECO:0000305|PubMed:2507523}.
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DR   EMBL; M22855; AAA22318.1; -; Genomic_DNA.
DR   EMBL; Z93932; CAB07900.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15162.1; -; Genomic_DNA.
DR   PIR; C33591; BVBSCB.
DR   RefSeq; NP_391052.1; NC_000964.3.
DR   RefSeq; WP_003243525.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; P14203; -.
DR   SMR; P14203; -.
DR   STRING; 224308.BSU31740; -.
DR   PaxDb; P14203; -.
DR   PRIDE; P14203; -.
DR   EnsemblBacteria; CAB15162; CAB15162; BSU_31740.
DR   GeneID; 937185; -.
DR   KEGG; bsu:BSU31740; -.
DR   PATRIC; fig|224308.179.peg.3440; -.
DR   eggNOG; COG3434; Bacteria.
DR   InParanoid; P14203; -.
DR   OMA; RQPIFNR; -.
DR   BioCyc; BSUB:BSU31740-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   Gene3D; 3.20.20.450; -; 1.
DR   InterPro; IPR014408; dGMP_Pdiesterase_EAL/HD-GYP.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR013976; HDOD.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF08668; HDOD; 1.
DR   PIRSF; PIRSF003180; DiGMPpdiest_YuxH; 1.
DR   SMART; SM00052; EAL; 1.
DR   SUPFAM; SSF141868; SSF141868; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS51833; HDOD; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..409
FT                   /note="Uncharacterized protein YuxH"
FT                   /id="PRO_0000049927"
FT   DOMAIN          1..209
FT                   /note="EAL"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00074"
FT   DOMAIN          203..392
FT                   /note="HDOD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01177"
SQ   SEQUENCE   409 AA;  47927 MW;  DF03E0BED6C014EC CRC64;
     MRVFVARQPI FNRKEQVVAY ELLYRESEEN VYSAKDGDQA TTDLVINSFL NIGIEKLTEG
     KRCFVNFTES LMFSNLPTSF NPKQLVIEIL EDIPITPALI SRCKELKKMG YMLALDDFYA
     INPQDEDLLE KLMSYIDILK IDFLKTTRME RRTILQTYGC RGLIFLAEKV ETRKEYKQAV
     QDGFQLFQGY FFSEPRIISG HDLSTHFYSY YELLNELSKE QPNIKRVTEY IERDLSLSYQ
     ILKFLNSSHS RLSQKIESIQ QAIMLLGFNE IKRWIYILSF KDLSRKGHSS KHEIIKISLI
     RAKLCELLAR KTSRPQPASY MLIGMFSLID TLLHREIEEI VQELPLKDEV GQALLGHQND
     YYQMLELVKL IESNNWDTCS ELGNQLDKEE AYECYLEALE WCHNLMDAK
 
 
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