YUXN_BACSU
ID YUXN_BACSU Reviewed; 291 AA.
AC P40950;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 15-JUL-1999, sequence version 2.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator YuxN;
GN Name=yuxN; OrderedLocusNames=BSU33030;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9639930; DOI=10.1099/00221287-144-6-1593;
RA Wipat A., Brignell C.S., Guy J.B., Rose M., Emmerson P.T., Harwood C.R.;
RT "The yvsA-yvqA (293 degrees - 289 degrees) region of the Bacillus subtilis
RT chromosome containing genes involved in metal ion uptake and a putative
RT sigma factor.";
RL Microbiology 144:1593-1600(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9353931; DOI=10.1099/00221287-143-10-3305;
RA Medina N., Vannier F., Roche B., Autret S., Levine A., Seror S.J.;
RT "Sequencing of regions downstream of addA (98 degrees) and citG (289
RT degrees) in Bacillus subtilis.";
RL Microbiology 143:3305-3308(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 204-291.
RC STRAIN=168;
RX PubMed=3923430; DOI=10.1093/nar/13.1.131;
RA Miles J.S., Guest J.R.;
RT "Complete nucleotide sequence of the fumarase gene (citG) of Bacillus
RT subtilis 168.";
RL Nucleic Acids Res. 13:131-140(1985).
RN [5]
RP REVIEW, AND GENE FAMILY.
RX PubMed=15944459; DOI=10.1128/mmbr.69.2.326-356.2005;
RA Ramos J.L., Martinez-Bueno M., Molina-Henares A.J., Teran W., Watanabe K.,
RA Zhang X., Gallegos M.T., Brennan R., Tobes R.;
RT "The TetR family of transcriptional repressors.";
RL Microbiol. Mol. Biol. Rev. 69:326-356(2005).
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB07974.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AJ223978; CAA11750.1; -; Genomic_DNA.
DR EMBL; Z93941; CAB07974.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL009126; CAB15293.1; -; Genomic_DNA.
DR EMBL; X01701; CAA25851.1; -; Genomic_DNA.
DR PIR; F70025; F70025.
DR RefSeq; NP_391183.1; NC_000964.3.
DR RefSeq; WP_003243192.1; NZ_JNCM01000033.1.
DR AlphaFoldDB; P40950; -.
DR SMR; P40950; -.
DR IntAct; P40950; 7.
DR STRING; 224308.BSU33030; -.
DR PaxDb; P40950; -.
DR PRIDE; P40950; -.
DR EnsemblBacteria; CAB15293; CAB15293; BSU_33030.
DR GeneID; 935945; -.
DR KEGG; bsu:BSU33030; -.
DR PATRIC; fig|224308.179.peg.3580; -.
DR eggNOG; COG1309; Bacteria.
DR InParanoid; P40950; -.
DR OMA; YTAELCF; -.
DR PhylomeDB; P40950; -.
DR BioCyc; BSUB:BSU33030-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..291
FT /note="Uncharacterized HTH-type transcriptional regulator
FT YuxN"
FT /id="PRO_0000070653"
FT DOMAIN 2..62
FT /note="HTH tetR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT DNA_BIND 25..44
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 291 AA; 33311 MW; 45A307340B0B9767 CRC64;
MKEKEKLIIE TALKLFAQKG YNSTSVQEIA KECKISKGAF YIYFPSKEAL LLSMLNYYYD
KTFTRILNIK TKGDSPRTAY RKQLTVLYEN ILEHKDFISM QLKEGSLPYT EEVEQCAKKI
RQSSLQFHID SLLNIYGKKA EPYTAELCFL IEGISQIYLE CMILLGYTVK PSQLADIIMN
RIDDMVKGMS ERNDKPFITL EEASSLFGPL THGRPDPLTE SIVKSLRDKI NSLNTNSSLE
LSESLDILEA EMKKKTPKLA IIKGMIHNLT ESEALAKDAE QLKYLLKQQH I