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YUXN_BACSU
ID   YUXN_BACSU              Reviewed;         291 AA.
AC   P40950;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 2.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YuxN;
GN   Name=yuxN; OrderedLocusNames=BSU33030;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9639930; DOI=10.1099/00221287-144-6-1593;
RA   Wipat A., Brignell C.S., Guy J.B., Rose M., Emmerson P.T., Harwood C.R.;
RT   "The yvsA-yvqA (293 degrees - 289 degrees) region of the Bacillus subtilis
RT   chromosome containing genes involved in metal ion uptake and a putative
RT   sigma factor.";
RL   Microbiology 144:1593-1600(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9353931; DOI=10.1099/00221287-143-10-3305;
RA   Medina N., Vannier F., Roche B., Autret S., Levine A., Seror S.J.;
RT   "Sequencing of regions downstream of addA (98 degrees) and citG (289
RT   degrees) in Bacillus subtilis.";
RL   Microbiology 143:3305-3308(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 204-291.
RC   STRAIN=168;
RX   PubMed=3923430; DOI=10.1093/nar/13.1.131;
RA   Miles J.S., Guest J.R.;
RT   "Complete nucleotide sequence of the fumarase gene (citG) of Bacillus
RT   subtilis 168.";
RL   Nucleic Acids Res. 13:131-140(1985).
RN   [5]
RP   REVIEW, AND GENE FAMILY.
RX   PubMed=15944459; DOI=10.1128/mmbr.69.2.326-356.2005;
RA   Ramos J.L., Martinez-Bueno M., Molina-Henares A.J., Teran W., Watanabe K.,
RA   Zhang X., Gallegos M.T., Brennan R., Tobes R.;
RT   "The TetR family of transcriptional repressors.";
RL   Microbiol. Mol. Biol. Rev. 69:326-356(2005).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAB07974.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AJ223978; CAA11750.1; -; Genomic_DNA.
DR   EMBL; Z93941; CAB07974.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AL009126; CAB15293.1; -; Genomic_DNA.
DR   EMBL; X01701; CAA25851.1; -; Genomic_DNA.
DR   PIR; F70025; F70025.
DR   RefSeq; NP_391183.1; NC_000964.3.
DR   RefSeq; WP_003243192.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; P40950; -.
DR   SMR; P40950; -.
DR   IntAct; P40950; 7.
DR   STRING; 224308.BSU33030; -.
DR   PaxDb; P40950; -.
DR   PRIDE; P40950; -.
DR   EnsemblBacteria; CAB15293; CAB15293; BSU_33030.
DR   GeneID; 935945; -.
DR   KEGG; bsu:BSU33030; -.
DR   PATRIC; fig|224308.179.peg.3580; -.
DR   eggNOG; COG1309; Bacteria.
DR   InParanoid; P40950; -.
DR   OMA; YTAELCF; -.
DR   PhylomeDB; P40950; -.
DR   BioCyc; BSUB:BSU33030-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS01081; HTH_TETR_1; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..291
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YuxN"
FT                   /id="PRO_0000070653"
FT   DOMAIN          2..62
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT   DNA_BIND        25..44
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   291 AA;  33311 MW;  45A307340B0B9767 CRC64;
     MKEKEKLIIE TALKLFAQKG YNSTSVQEIA KECKISKGAF YIYFPSKEAL LLSMLNYYYD
     KTFTRILNIK TKGDSPRTAY RKQLTVLYEN ILEHKDFISM QLKEGSLPYT EEVEQCAKKI
     RQSSLQFHID SLLNIYGKKA EPYTAELCFL IEGISQIYLE CMILLGYTVK PSQLADIIMN
     RIDDMVKGMS ERNDKPFITL EEASSLFGPL THGRPDPLTE SIVKSLRDKI NSLNTNSSLE
     LSESLDILEA EMKKKTPKLA IIKGMIHNLT ESEALAKDAE QLKYLLKQQH I
 
 
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