CC038_MOUSE
ID CC038_MOUSE Reviewed; 348 AA.
AC Q3TTL0; A9C482; Q8VE03;
DT 11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Uncharacterized protein C3orf38 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Czech II; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May be involved in apoptosis regulation. {ECO:0000250}.
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DR EMBL; AK161311; BAE36315.1; -; mRNA.
DR EMBL; CT030641; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC020029; AAH20029.1; -; mRNA.
DR CCDS; CCDS28265.1; -.
DR RefSeq; NP_080549.1; NM_026273.2.
DR AlphaFoldDB; Q3TTL0; -.
DR IntAct; Q3TTL0; 1.
DR STRING; 10090.ENSMUSP00000076255; -.
DR iPTMnet; Q3TTL0; -.
DR PhosphoSitePlus; Q3TTL0; -.
DR EPD; Q3TTL0; -.
DR jPOST; Q3TTL0; -.
DR MaxQB; Q3TTL0; -.
DR PaxDb; Q3TTL0; -.
DR PRIDE; Q3TTL0; -.
DR Antibodypedia; 32056; 62 antibodies from 14 providers.
DR Ensembl; ENSMUST00000076991; ENSMUSP00000076255; ENSMUSG00000059920.
DR GeneID; 67609; -.
DR KEGG; mmu:67609; -.
DR UCSC; uc007zqb.1; mouse.
DR MGI; MGI:1914859; 4930453N24Rik.
DR VEuPathDB; HostDB:ENSMUSG00000059920; -.
DR eggNOG; ENOG502RKN5; Eukaryota.
DR GeneTree; ENSGT00390000000367; -.
DR HOGENOM; CLU_060119_0_0_1; -.
DR InParanoid; Q3TTL0; -.
DR OMA; CGTNEVR; -.
DR OrthoDB; 1399225at2759; -.
DR PhylomeDB; Q3TTL0; -.
DR TreeFam; TF323327; -.
DR BioGRID-ORCS; 67609; 3 hits in 72 CRISPR screens.
DR PRO; PR:Q3TTL0; -.
DR Proteomes; UP000000589; Chromosome 16.
DR RNAct; Q3TTL0; protein.
DR Bgee; ENSMUSG00000059920; Expressed in seminiferous tubule of testis and 249 other tissues.
DR Genevisible; Q3TTL0; MM.
DR GO; GO:0005634; C:nucleus; ISO:MGI.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0043065; P:positive regulation of apoptotic process; ISO:MGI.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR026698; UPF_C3orf38.
DR PANTHER; PTHR21084; PTHR21084; 1.
DR Pfam; PF15008; DUF4518; 1.
DR SUPFAM; SSF54427; SSF54427; 1.
PE 2: Evidence at transcript level;
KW Apoptosis; Reference proteome.
FT CHAIN 1..348
FT /note="Uncharacterized protein C3orf38 homolog"
FT /id="PRO_0000244990"
FT CONFLICT 123
FT /note="Missing (in Ref. 3; AAH20029)"
FT /evidence="ECO:0000305"
FT CONFLICT 316
FT /note="Q -> P (in Ref. 3; AAH20029)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 348 AA; 39532 MW; 1B99382818A9EF8C CRC64;
MSGLSHLESE GCRNLLGLLD NDEIMALCDT VTNRLVQPVD RQDAIHAILV YSQNVEELLR
RKKVHREVIF KYLAKQGVVV PPTAEKHNLI QYAKDYWAKQ SPKLKDTAEP VTKTEDIQLF
KQQAKEDKEA EKVDFRRLGE EFCHWFFELL NSQNPFLGPP QDDWGPQHFW HDAKLRFYYN
TSEQNTTDYQ GAEIVSLRLL SLVKEEFLFL SPNLDSQGLK CASSPHGLVM VGVAGTVHRG
NSCLGIFEQI FGLIRSPFVE NTWKIKFINL RIIGGSSLAP ESVLKPSVTF EPSDLEAFYN
VITLCNSPEV RPNVRQIIDS GTGDQVLHSG DEALLNKREM NLLTPLKH
