ID   YVAQ_BACSU              Reviewed;         566 AA.
AC   O32239;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Putative sensory transducer protein YvaQ;
DE   AltName: Full=Methyl-accepting chemotaxis protein;
DE   Flags: Precursor;
GN   Name=yvaQ; OrderedLocusNames=BSU33690;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Chemotactic-signal transducers respond to changes in the
CC       concentration of attractants and repellents in the environment,
CC       transduce a signal from the outside to the inside of the cell, and
CC       facilitate sensory adaptation through the variation of the level of
CC       methylation. Attractants increase the level of methylation while
CC       repellents decrease the level of methylation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000305}.
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DR   EMBL; AL009126; CAB15374.1; -; Genomic_DNA.
DR   PIR; F70028; F70028.
DR   RefSeq; NP_391249.1; NC_000964.3.
DR   RefSeq; WP_003228375.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; O32239; -.
DR   SMR; O32239; -.
DR   IntAct; O32239; 10.
DR   STRING; 224308.BSU33690; -.
DR   jPOST; O32239; -.
DR   PaxDb; O32239; -.
DR   PRIDE; O32239; -.
DR   EnsemblBacteria; CAB15374; CAB15374; BSU_33690.
DR   GeneID; 938479; -.
DR   KEGG; bsu:BSU33690; -.
DR   PATRIC; fig|224308.179.peg.3654; -.
DR   eggNOG; COG0840; Bacteria.
DR   InParanoid; O32239; -.
DR   OMA; RSIENIH; -.
DR   PhylomeDB; O32239; -.
DR   BioCyc; BSUB:BSU33690-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Coiled coil; Membrane; Reference proteome; Signal;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000255"
FT   CHAIN           32..566
FT                   /note="Putative sensory transducer protein YvaQ"
FT                   /id="PRO_0000388355"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          208..261
FT                   /note="HAMP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00102"
FT   DOMAIN          280..530
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00284"
FT   COILED          74..110
FT                   /evidence="ECO:0000255"
FT   COILED          536..566
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   566 AA;  62831 MW;  32E507C04B2C2B89 CRC64;
     MRLTISRKFS LVFLTLILIN LLVGGIGVLN MQHIIQKTDE INTKWIDGIK GITSINYVTE
     HLSSKEKDFL IYTDKSKMDT LDQEMNQIME DINQKLDNYE KTISTDKEQK LFEQLQTKVN
     TYMDIHAQII ESGRTNDMDK ARGLLVQTEA SFEDMKKTIT QLVDLNQEGS NTAVKETKAV
     YHKGLIYTAL LVAASILISI FIWLYITRNI VKPIIRMKES ANHIAEGDLS NDMEALNSKD
     ELGDLNEALQ KMVGNLRDIV GYSKDISSRV LSSSQVLATA TNETRSGSKH ITETMNEMAE
     GSEQQAQDAV TIAESMNEFT ESIDKAYNHG ITISDTSQNV LELAVSGNEN MATSLQQMKT
     IHHIVEEAVH KVRSLEQHSQ DINKLVQVIN GIAEQTNLLS LNAAIEAARA GESGKGFAVV
     AEEVRKLADG VSDSVQDITR IVNGTQQEIH TVITYLESSF TEVEKGTENL TDTGQAMQHI
     KQSVTHVADS IKEVTDGLKQ LTNQSITINQ SIENIASVSE ESAAGIEETF SITEQSAHSM
     DQVLLNAEEL EQLANELNEK MGQFTI