CC080_MOUSE
ID CC080_MOUSE Reviewed; 247 AA.
AC E9Q0B3; Q8C4H3;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-APR-2011, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Uncharacterized membrane protein C3orf80 homolog;
DE Flags: Precursor;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 46-247.
RC STRAIN=C57BL/6J; TISSUE=Cerebellum;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AC115062; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK082199; BAC38434.1; -; mRNA.
DR CCDS; CCDS50931.1; -.
DR RefSeq; NP_001161468.1; NM_001167996.1.
DR AlphaFoldDB; E9Q0B3; -.
DR PhosphoSitePlus; E9Q0B3; -.
DR PaxDb; E9Q0B3; -.
DR PRIDE; E9Q0B3; -.
DR Antibodypedia; 50240; 4 antibodies from 4 providers.
DR Ensembl; ENSMUST00000054551; ENSMUSP00000056782; ENSMUSG00000046999.
DR GeneID; 68725; -.
DR KEGG; mmu:68725; -.
DR UCSC; uc012cqj.1; mouse.
DR MGI; MGI:1915975; 1110032F04Rik.
DR VEuPathDB; HostDB:ENSMUSG00000046999; -.
DR eggNOG; ENOG502S2DR; Eukaryota.
DR GeneTree; ENSGT00390000005823; -.
DR HOGENOM; CLU_1363090_0_0_1; -.
DR InParanoid; E9Q0B3; -.
DR OMA; TEVKCCK; -.
DR OrthoDB; 1385214at2759; -.
DR TreeFam; TF337543; -.
DR BioGRID-ORCS; 68725; 1 hit in 72 CRISPR screens.
DR PRO; PR:E9Q0B3; -.
DR Proteomes; UP000000589; Chromosome 3.
DR RNAct; E9Q0B3; protein.
DR Bgee; ENSMUSG00000046999; Expressed in lumbar dorsal root ganglion and 98 other tissues.
DR Genevisible; E9Q0B3; MM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR031696; DUF4719.
DR PANTHER; PTHR38505; PTHR38505; 1.
DR Pfam; PF15843; DUF4719; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..35
FT /evidence="ECO:0000255"
FT CHAIN 36..247
FT /note="Uncharacterized membrane protein C3orf80 homolog"
FT /id="PRO_0000413692"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 109..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 247 AA; 25757 MW; 47BFE84A99C0E252 CRC64;
MWGPGVTAEG LSVAPAPPPL LPLLLLLALA LVAPSRGGGG CAELACGERE RCCDSANATA
VRCCKLPLHA FLDNVGWFVR KLSGLLILLV LFAIGYFLQR IICPSPRRYP RGQARPGQAR
PGPPGGAGPP GTAGPPDDDD DSPALLRDEV AAGSQDSLLD SGGGRGRGSG GRLPPSCVSE
HELHVVSPVF LQLPSYEEVK YLPTYEESMR LQQLSPAEVV LPVSVLGRPR GGSAGDSDGG
QVRFPLI
