ID   YW12_CAEEL              Reviewed;         396 AA.
AC   Q22306; A0FLR0; Q6BEU9;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 3.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=UPF0046 protein T07D4.2;
GN   ORFNames=T07D4.2;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- INTERACTION:
CC       Q22306; Q19980: cat-4; NbExp=2; IntAct=EBI-311847, EBI-311852;
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=b;
CC         IsoId=Q22306-1; Sequence=Displayed;
CC       Name=a;
CC         IsoId=Q22306-2; Sequence=VSP_026508;
CC       Name=c;
CC         IsoId=Q22306-3; Sequence=VSP_026509;
CC   -!- SIMILARITY: Belongs to the UPF0046 family. {ECO:0000305}.
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DR   EMBL; Z50071; CAA90405.3; -; Genomic_DNA.
DR   EMBL; Z50071; CAH04718.2; -; Genomic_DNA.
DR   EMBL; Z50071; CAL64000.2; -; Genomic_DNA.
DR   PIR; T24660; T24660.
DR   RefSeq; NP_001022323.2; NM_001027152.2. [Q22306-2]
DR   RefSeq; NP_001022324.2; NM_001027153.3. [Q22306-1]
DR   RefSeq; NP_001076633.1; NM_001083164.3. [Q22306-3]
DR   AlphaFoldDB; Q22306; -.
DR   SMR; Q22306; -.
DR   BioGRID; 39743; 11.
DR   DIP; DIP-26139N; -.
DR   IntAct; Q22306; 7.
DR   STRING; 6239.T07D4.2b; -.
DR   EPD; Q22306; -.
DR   PaxDb; Q22306; -.
DR   PeptideAtlas; Q22306; -.
DR   EnsemblMetazoa; T07D4.2a.1; T07D4.2a.1; WBGene00011579. [Q22306-2]
DR   EnsemblMetazoa; T07D4.2b.1; T07D4.2b.1; WBGene00011579. [Q22306-1]
DR   EnsemblMetazoa; T07D4.2c.1; T07D4.2c.1; WBGene00011579. [Q22306-3]
DR   GeneID; 174416; -.
DR   KEGG; cel:CELE_T07D4.2; -.
DR   UCSC; T07D4.2b; c. elegans. [Q22306-1]
DR   CTD; 174416; -.
DR   WormBase; T07D4.2a; CE40620; WBGene00011579; -. [Q22306-2]
DR   WormBase; T07D4.2b; CE40621; WBGene00011579; -. [Q22306-1]
DR   WormBase; T07D4.2c; CE40622; WBGene00011579; -. [Q22306-3]
DR   eggNOG; KOG3947; Eukaryota.
DR   GeneTree; ENSGT00390000007681; -.
DR   InParanoid; Q22306; -.
DR   OMA; KLRVVCM; -.
DR   OrthoDB; 1301937at2759; -.
DR   PhylomeDB; Q22306; -.
DR   PRO; PR:Q22306; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00011579; Expressed in larva and 2 other tissues.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   Pfam; PF00149; Metallophos; 1.
DR   SUPFAM; SSF56300; SSF56300; 1.
PE   1: Evidence at protein level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..396
FT                   /note="UPF0046 protein T07D4.2"
FT                   /id="PRO_0000053410"
FT   REGION          73..94
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..95
FT                   /note="MLSPALLKVSLNRRSSAPVPQDEKMMFHSRNRAASYLQPMIEDQELIGFNRD
FT                   RRRSSGSIIVDSFELGNASPSRRGSIASGIPMDKKTRRKLSNP -> MFSKSSNRFGTT
FT                   SIFGDQSIKDEYRNRQRRLSLIGGPISGTSPNRRESLVRELRT (in isoform a)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_026508"
FT   VAR_SEQ         1..24
FT                   /note="Missing (in isoform c)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_026509"
SQ   SEQUENCE   396 AA;  44869 MW;  C4C9FCE2368484D1 CRC64;
     MLSPALLKVS LNRRSSAPVP QDEKMMFHSR NRAASYLQPM IEDQELIGFN RDRRRSSGSI
     IVDSFELGNA SPSRRGSIAS GIPMDKKTRR KLSNPVSLHQ YTEDPTLAWE MLKEKRPVKP
     VRQMRLDTPV KPDHVRFVCI GCTHGEQFDI SKLPPGDVLL VAGDFTSCGL PNEVHNFNKL
     LGKLKYSYKV VIGGNHECTF DDTFLKLKQE SEPKEMALKQ ALLSAIHSDS KGGISAKDLL
     SNAIYLEDNV IELFGITIYG TPWQPKVDNW AFNLSRGQQL LDKWNLIPAG VDVLLTHTPP
     LGHGDMMNNG QRMGCAELLN TVFKRVRPKY HVFGHIHEGY GCTTDGYTKF INCCMCNENL
     DLKNEPVIFD IPVHPHTKQF YIQNVKKIHK RFQKKK