YWBF_BACSU
ID YWBF_BACSU Reviewed; 399 AA.
AC P39589;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Uncharacterized transporter YwbF;
GN Name=ywbF; OrderedLocusNames=BSU38340; ORFNames=ipa-21r;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=7934828; DOI=10.1111/j.1365-2958.1993.tb01963.x;
RA Glaser P., Kunst F., Arnaud M., Coudart M.P., Gonzales W., Hullo M.-F.,
RA Ionescu M., Lubochinsky B., Marcelino L., Moszer I., Presecan E.,
RA Santana M., Schneider E., Schweizer J., Vertes A., Rapoport G., Danchin A.;
RT "Bacillus subtilis genome project: cloning and sequencing of the 97 kb
RT region from 325 degrees to 333 degrees.";
RL Mol. Microbiol. 10:371-384(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000305}.
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DR EMBL; X73124; CAA51577.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB15860.1; -; Genomic_DNA.
DR PIR; S39676; S39676.
DR RefSeq; NP_391713.1; NC_000964.3.
DR RefSeq; WP_003242781.1; NZ_JNCM01000034.1.
DR AlphaFoldDB; P39589; -.
DR SMR; P39589; -.
DR STRING; 224308.BSU38340; -.
DR PaxDb; P39589; -.
DR PRIDE; P39589; -.
DR EnsemblBacteria; CAB15860; CAB15860; BSU_38340.
DR GeneID; 937325; -.
DR KEGG; bsu:BSU38340; -.
DR PATRIC; fig|224308.179.peg.4150; -.
DR eggNOG; COG2814; Bacteria.
DR InParanoid; P39589; -.
DR OMA; HGPYYTF; -.
DR PhylomeDB; P39589; -.
DR BioCyc; BSUB:BSU38340-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0030395; F:lactose binding; IBA:GO_Central.
DR GO; GO:0015528; F:lactose:proton symporter activity; IBA:GO_Central.
DR GO; GO:0071702; P:organic substance transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 2.
DR InterPro; IPR026032; HcaT.
DR InterPro; IPR024989; MFS_assoc_dom.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF12832; MFS_1_like; 1.
DR PIRSF; PIRSF004925; HcaT; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Symport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..399
FT /note="Uncharacterized transporter YwbF"
FT /id="PRO_0000196192"
FT TOPO_DOM 1..8
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 9..35
FT /note="Helical; Name=1"
FT /evidence="ECO:0000250"
FT TOPO_DOM 36..42
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 43..71
FT /note="Helical; Name=2"
FT /evidence="ECO:0000250"
FT TOPO_DOM 72..75
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 76..101
FT /note="Helical; Name=3"
FT /evidence="ECO:0000250"
FT TOPO_DOM 102..105
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 106..123
FT /note="Helical; Name=4"
FT /evidence="ECO:0000250"
FT TOPO_DOM 124..134
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 135..157
FT /note="Helical; Name=5"
FT /evidence="ECO:0000250"
FT TOPO_DOM 158..160
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 161..180
FT /note="Helical; Name=6"
FT /evidence="ECO:0000250"
FT TOPO_DOM 181..210
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 211..230
FT /note="Helical; Name=7"
FT /evidence="ECO:0000250"
FT TOPO_DOM 231..234
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 235..259
FT /note="Helical; Name=8"
FT /evidence="ECO:0000250"
FT TOPO_DOM 260..269
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 270..289
FT /note="Helical; Name=9"
FT /evidence="ECO:0000250"
FT TOPO_DOM 290..292
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 293..315
FT /note="Helical; Name=10"
FT /evidence="ECO:0000250"
FT TOPO_DOM 316..327
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 328..355
FT /note="Helical; Name=11"
FT /evidence="ECO:0000250"
FT TOPO_DOM 356..358
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 359..379
FT /note="Helical; Name=12"
FT /evidence="ECO:0000250"
FT TOPO_DOM 380..399
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
SQ SEQUENCE 399 AA; 44009 MW; 2811743513D9CBD9 CRC64;
MHNLQVRRHY AALKGFYLFA FLGTGSIIPL LSMYLTKEQH LSGSQVGLIM SLGPIVMIFF
QPFWGMLSDY TQKTKGLLAV CTSITGIIGL AYIAFDSFPL FILIAACFAA FQSTIIPLSD
SISLRYTQET NGNYGGIRLF GSLGFGVAVF AMGQVTNQLY PIHVIFIFGC AFLCIAAILA
SQVPGQQKTT KVNIRKGFRE LISNKTFLIF MIITFTTFAP NLANNTYFSL FLDKSGASLS
AIGILFFIGV ISEIPFMRFA QTFIDKMGLL NVIMLSGGVS LFRWALYFTA PSLWIIYATV
FLQGVAIGLF IPAALQYVKK ITPRHVEATA LTMYAAIGNG FGNWFCTFAG GYIFDYVSIF
AVYLLFGILS IAGFGLTLYL MKAEKNKHTL HQPAVTFKP
