ID   YWQA_BACSU              Reviewed;         922 AA.
AC   P94593; P96713; Q798L9;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 2.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Uncharacterized ATP-dependent helicase YwqA;
DE            EC=3.6.4.-;
GN   Name=ywqA; OrderedLocusNames=BSU36280;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 56-922.
RC   STRAIN=168;
RX   PubMed=9353933; DOI=10.1099/00221287-143-10-3313;
RA   Presecan E., Moszer I., Boursier L., Cruz Ramos H., De La Fuente V.,
RA   Hullo M.-F., Lelong C., Schleich S., Sekowska A., Song B.H., Villani G.,
RA   Kunst F., Danchin A., Glaser P.;
RT   "The Bacillus subtilis genome from gerBC (311 degrees) to licR (334
RT   degrees).";
RL   Microbiology 143:3313-3328(1997).
RN   [3]
RP   SUBUNIT.
RC   STRAIN=168;
RX   PubMed=21710567; DOI=10.1002/pmic.201000790;
RA   Delumeau O., Lecointe F., Muntel J., Guillot A., Guedon E., Monnet V.,
RA   Hecker M., Becher D., Polard P., Noirot P.;
RT   "The dynamic protein partnership of RNA polymerase in Bacillus subtilis.";
RL   Proteomics 11:2992-3001(2011).
CC   -!- SUBUNIT: Interacts with the RNA polymerase core.
CC       {ECO:0000269|PubMed:21710567}.
CC   -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family. {ECO:0000305}.
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DR   EMBL; AL009126; CAB15645.1; -; Genomic_DNA.
DR   EMBL; Z83337; CAB05939.1; -; Genomic_DNA.
DR   PIR; D70066; D70066.
DR   RefSeq; NP_391509.1; NC_000964.3.
DR   RefSeq; WP_003227803.1; NZ_JNCM01000034.1.
DR   AlphaFoldDB; P94593; -.
DR   SMR; P94593; -.
DR   STRING; 224308.BSU36280; -.
DR   PaxDb; P94593; -.
DR   PRIDE; P94593; -.
DR   EnsemblBacteria; CAB15645; CAB15645; BSU_36280.
DR   GeneID; 936906; -.
DR   KEGG; bsu:BSU36280; -.
DR   PATRIC; fig|224308.179.peg.3927; -.
DR   eggNOG; COG0553; Bacteria.
DR   InParanoid; P94593; -.
DR   OMA; TQYIQMG; -.
DR   PhylomeDB; P94593; -.
DR   BioCyc; BSUB:BSU36280-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008094; F:ATP-dependent activity, acting on DNA; IBA:GO_Central.
DR   GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.10810; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR022138; Helicase_SWF/SNF-rel.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR000330; SNF2_N.
DR   Pfam; PF12419; DUF3670; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00176; SNF2-rel_dom; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..922
FT                   /note="Uncharacterized ATP-dependent helicase YwqA"
FT                   /id="PRO_0000388352"
FT   DOMAIN          462..625
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   DOMAIN          753..907
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT   MOTIF           576..579
FT                   /note="DEAQ box"
FT   BINDING         475..482
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ   SEQUENCE   922 AA;  106029 MW;  89F6B2A28D70B4A5 CRC64;
     MASLKEILIH VEQMEDGSFT LSAFDENEQP LPYSHMKKHL FQWHESSFYG TFLEDVSFIG
     TTAVLLSPWM TVELLGKNSF NSFSSVQLTE ETEPLIEAAS TIYEFIADGD FMPDYDAWTN
     GVFRWKDRDN ILEGFTAEWF SAAVQDYIQY DDDLREKWEH IKEKSPAVTT FRGHFLDEED
     FLEGIGWIDD QSPFTVGLRL NEPDFDGDEW KIEMFLRDKK SGAVEFFDGL KSLKKSWQAY
     SDKIAREQDR FHRTVPWLSF DSGTTLISEE EAWIFLSEAS ETLVDMGVEI LLPSWWQIVR
     DSNMMLKAKV SSSPRGESFV GMNALLDFNW RFATNGIELT EAEFNELVAS NRRLVNIRGQ
     WVKIDPQFIK QMKRLMEKAE SEGLHMSDIL ARELMDQQDG GLEDSDLIDT SAFAGIQFDL
     SKQLRSLIRK LTAAENLPEH KVSPSFKGTL RPYQKYGMNW LLFLRESGFG ACLADDMGLG
     KTIQMIAYFL HVKESGRQKT PHLIIAPTSV LGNWQRELQT FAPDLSVALH YGPRRPKGDD
     FAAHYENADV VLTSYGLSHA DTEELSSVTW NTICLDEAQN IKNAHTKQSR AIRKLKGLHH
     IALSGTPMEN RLTELWSIFD FMNKGYLGSL TGFHKRYVLP IEKDRDEKRI GQLQQLIRPF
     LLRRTKRDEE VALNLPEKLE EKEFIPLSAE QASLYEQLVK DTFDHMTSLT GMQRKALILS
     MLGRLKQICD HPALYLKEEQ TELLAGRSVK LEKLLELMTA IRAQNESCLI FTQYIQMGNM
     MKRLLEKTFG EPVQFLNGSL SKQERDTLVE KFQRKEYPTL ILSLKAGGTG LNLTAANHVI
     HYDRWWNPAV ENQATDRAYR IGQERFVHVH KMITTGTIEE KIDVMLESKQ TLNDQIIQSE
     NWITELSTQE LEELFTLSAT AQ