CC110_MACFA
ID CC110_MACFA Reviewed; 833 AA.
AC Q95JS9; Q95K11;
DT 05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 2.
DT 25-MAY-2022, entry version 43.
DE RecName: Full=Coiled-coil domain-containing protein 110;
GN Name=CCDC110; ORFNames=QtsA-11294, QtsA-13715;
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Testis;
RX PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA Terao K., Sugano S., Hashimoto K.;
RT "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT the human genome sequence.";
RL BMC Genomics 3:36-36(2002).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q95JS9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q95JS9-2; Sequence=VSP_020366;
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DR EMBL; AB070016; BAB62961.1; -; mRNA.
DR EMBL; AB070100; BAB63045.1; -; mRNA.
DR AlphaFoldDB; Q95JS9; -.
DR SMR; Q95JS9; -.
DR STRING; 9541.XP_005556488.1; -.
DR eggNOG; ENOG502QR3F; Eukaryota.
DR Proteomes; UP000233100; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Nucleus; Reference proteome.
FT CHAIN 1..833
FT /note="Coiled-coil domain-containing protein 110"
FT /id="PRO_0000249077"
FT COILED 431..778
FT /evidence="ECO:0000255"
FT VAR_SEQ 822..833
FT /note="YLKVKDRTLKHH -> IPSKLYQLLPSKIYK (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12498619"
FT /id="VSP_020366"
FT CONFLICT 563
FT /note="E -> G (in Ref. 1; BAB62961)"
FT /evidence="ECO:0000305"
FT CONFLICT 699
FT /note="K -> E (in Ref. 1; BAB63045)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 833 AA; 96599 MW; 4599149201C91F7E CRC64;
MSPEKQPQEE DEVDSVLLSA SKILNSSEGV KESGCSGTEY GCIAESENQI QPQSALKVLQ
HQLESFQALR MQTLQNVSMV QSEISEILNK SIIEVENPQF GSEKNLAFGA RIEKDLPTEN
QEGNLSMEKS RHFKDSKTLH SVEEKLSGDS VNSLSQNINV PSQMHFEDTL TLRTSTDNLS
SNIIIHPSEN SDILKNYNNF YHFLPTAPQN VMSQADTVIL DKSKITVPFL KHGFCENLDD
ICHSIEQMKE ELQKSHDREV ALANELQTLK TDPNVQSNDK YDLSPIHQEK MNFIKEENMD
GNLNEDIKSK RISELEALVN KLLPFRETVS KFHVNFCRKC KKLSKSEIHR GKRNEKNNKE
IPITGKNITD LKFHSRVPRY TLSFLDQTKH EMKDKERQPF LVKQGSIIFE NEKTSKVNSV
TEQCVAKIQY LQNYLKESVQ IQKKVTELEN ENLNLKSKMK PLIFTTQSLI QKVETYEKQL
KNLVEEKSTI QSKLSKTEED SKECLKELKK IIGKYNVLQG QNKTLEEKNI QLSLEKQQMM
EAFDQLKSKE HKTQSDMAIV NNENNLMSIE MEAMKTNILL IQDEKEMLEK KTHQLLKEKS
SLENELKENQ LEVMQLKEKE RLAKTEQETL LQIIETVKDE KLNLETTLQE SAAARQIMER
EIENIQTYQS TAEENFLQEI KNAKSEASIY KNSLSEIGKE CEMLSKMVME TKTDNQILKE
ELKKHSQENV KFENSISRLT EDKILLENYV RSIENERDTL EFEMRNLQRE YLNLSDKICS
QHNDPSKSTY ISRREKFHFD NYIHEDISSP RSRPLASDLK GYLKVKDRTL KHH