ID   YWS1_CAEEL              Reviewed;         292 AA.
AC   Q10937; A8WFJ3; A8WFJ4;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 2.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Uncharacterized protein B0310.1;
GN   ORFNames=B0310.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=a;
CC         IsoId=Q10937-1; Sequence=Displayed;
CC       Name=b;
CC         IsoId=Q10937-2; Sequence=VSP_032730, VSP_032731;
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DR   EMBL; FO080169; CCD61753.1; -; Genomic_DNA.
DR   EMBL; FO080169; CCD61754.1; -; Genomic_DNA.
DR   PIR; T15325; T15325.
DR   RefSeq; NP_001123087.1; NM_001129615.1. [Q10937-2]
DR   RefSeq; NP_001123088.1; NM_001129616.3.
DR   AlphaFoldDB; Q10937; -.
DR   SMR; Q10937; -.
DR   EPD; Q10937; -.
DR   PaxDb; Q10937; -.
DR   PeptideAtlas; Q10937; -.
DR   EnsemblMetazoa; B0310.1a.1; B0310.1a.1; WBGene00015137. [Q10937-2]
DR   EnsemblMetazoa; B0310.1b.1; B0310.1b.1; WBGene00015137. [Q10937-1]
DR   GeneID; 181922; -.
DR   UCSC; B0310.1b; c. elegans. [Q10937-1]
DR   CTD; 181922; -.
DR   WormBase; B0310.1a; CE41749; WBGene00015137; -. [Q10937-2]
DR   WormBase; B0310.1b; CE41750; WBGene00015137; -. [Q10937-1]
DR   eggNOG; KOG1418; Eukaryota.
DR   HOGENOM; CLU_953880_0_0_1; -.
DR   InParanoid; Q10937; -.
DR   OMA; AQSEHEW; -.
DR   OrthoDB; 1007449at2759; -.
DR   PhylomeDB; Q10937; -.
DR   PRO; PR:Q10937; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00015137; Expressed in larva and 4 other tissues.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0015271; F:outward rectifier potassium channel activity; IBA:GO_Central.
DR   GO; GO:0022841; F:potassium ion leak channel activity; IBA:GO_Central.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0030322; P:stabilization of membrane potential; IBA:GO_Central.
DR   InterPro; IPR003280; 2pore_dom_K_chnl.
DR   PANTHER; PTHR11003; PTHR11003; 1.
PE   4: Predicted;
KW   Alternative splicing; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..292
FT                   /note="Uncharacterized protein B0310.1"
FT                   /id="PRO_0000065069"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          267..292
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        267..282
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..28
FT                   /note="Missing (in isoform b)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_032730"
FT   VAR_SEQ         29..43
FT                   /note="IGMILFPALCTPAVK -> MRNSACLAKIHFNKI (in isoform b)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_032731"
SQ   SEQUENCE   292 AA;  33007 MW;  FD16B773E022FD1C CRC64;
     MGADLPPKFQ YAFRRCLFYT FVLVAWLFIG MILFPALCTP AVKQDDNEAG IFRLDAKRSD
     LLNVLWAETI TNGEDDWSEL ADQKLELYEK ALLQHYGIDL DKSDKSFASG LQKSFAISTT
     IGPLDVDDFT TLGKLIAVLY ALIGTPLFLT VIGQLGKMVT SVWQGTTLWI VTIVYIFISA
     VIYDIVEGGS DDVPFIEAIF SIFLQFTTVG EVDNEFHGVL PYCIVVLGLA LITALYQEMQ
     HNIERFIHPF EYSFNRLCGN VERWAGEKSE DKKSIVTSRI EEENEDEISD YE