YXAF_BACSU
ID YXAF_BACSU Reviewed; 191 AA.
AC P42105;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator YxaF;
GN Name=yxaF; OrderedLocusNames=BSU39990; ORFNames=S14F;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / BGSC1A1;
RX PubMed=7584049; DOI=10.1093/dnares/2.2.61;
RA Yoshida K., Seki S., Fujimura M., Miwa Y., Fujita Y.;
RT "Cloning and sequencing of a 36-kb region of the Bacillus subtilis genome
RT between the gnt and iol operons.";
RL DNA Res. 2:61-69(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP SEQUENCE REVISION TO 19.
RX PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT 168 reference genome a decade later.";
RL Microbiology 155:1758-1775(2009).
RN [4]
RP REVIEW, AND GENE FAMILY.
RX PubMed=15944459; DOI=10.1128/mmbr.69.2.326-356.2005;
RA Ramos J.L., Martinez-Bueno M., Molina-Henares A.J., Teran W., Watanabe K.,
RA Zhang X., Gallegos M.T., Brennan R., Tobes R.;
RT "The TetR family of transcriptional repressors.";
RL Microbiol. Mol. Biol. Rev. 69:326-356(2005).
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DR EMBL; AB005554; BAA21585.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB16036.2; -; Genomic_DNA.
DR PIR; E70071; E70071.
DR RefSeq; NP_391879.2; NC_000964.3.
DR RefSeq; WP_003227022.1; NZ_JNCM01000034.1.
DR PDB; 1SGM; X-ray; 2.00 A; A/B=1-191.
DR PDBsum; 1SGM; -.
DR AlphaFoldDB; P42105; -.
DR SMR; P42105; -.
DR STRING; 224308.BSU39990; -.
DR PaxDb; P42105; -.
DR PRIDE; P42105; -.
DR EnsemblBacteria; CAB16036; CAB16036; BSU_39990.
DR GeneID; 937690; -.
DR KEGG; bsu:BSU39990; -.
DR PATRIC; fig|224308.179.peg.4325; -.
DR eggNOG; COG1309; Bacteria.
DR InParanoid; P42105; -.
DR OMA; EIDGWFE; -.
DR PhylomeDB; P42105; -.
DR BioCyc; BSUB:BSU39990-MON; -.
DR EvolutionaryTrace; P42105; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF48498; SSF48498; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-binding; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..191
FT /note="Uncharacterized HTH-type transcriptional regulator
FT YxaF"
FT /id="PRO_0000070655"
FT DOMAIN 5..65
FT /note="HTH tetR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT DNA_BIND 28..47
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT CONFLICT 19
FT /note="F -> S (in Ref. 1; BAA21585)"
FT /evidence="ECO:0000305"
FT HELIX 7..22
FT /evidence="ECO:0007829|PDB:1SGM"
FT TURN 24..26
FT /evidence="ECO:0007829|PDB:1SGM"
FT HELIX 29..36
FT /evidence="ECO:0007829|PDB:1SGM"
FT HELIX 42..45
FT /evidence="ECO:0007829|PDB:1SGM"
FT TURN 47..49
FT /evidence="ECO:0007829|PDB:1SGM"
FT HELIX 51..75
FT /evidence="ECO:0007829|PDB:1SGM"
FT HELIX 80..93
FT /evidence="ECO:0007829|PDB:1SGM"
FT HELIX 98..100
FT /evidence="ECO:0007829|PDB:1SGM"
FT HELIX 107..113
FT /evidence="ECO:0007829|PDB:1SGM"
FT HELIX 118..141
FT /evidence="ECO:0007829|PDB:1SGM"
FT HELIX 146..170
FT /evidence="ECO:0007829|PDB:1SGM"
FT HELIX 174..180
FT /evidence="ECO:0007829|PDB:1SGM"
FT HELIX 183..186
FT /evidence="ECO:0007829|PDB:1SGM"
SQ SEQUENCE 191 AA; 21079 MW; 2D35F49F1F60EF4F CRC64;
MTSRGDSREK ILHTASRLFQ LQGYHATGLN QIVKESGAPK GSLYHFFPNG KEELAIEAVT
YTGKIVEHLI QQSMDESSDP VEAIQLFIKK TASQFDNTES IKGIPVGLLA SETALISEPL
RTVCMKVFKS WEAVFARKLM ENGFAEEEAN QLGTLINSMI EGGIMLSLTN KDKTPLLLIA
EQIPVLVRKK G
