ID   CC113_BOVIN             Reviewed;         391 AA.
AC   Q3SZX9;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Coiled-coil domain-containing protein 113;
GN   Name=CCDC113;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX   PubMed=25074808; DOI=10.1242/jcs.157008;
RA   Firat-Karalar E.N., Sante J., Elliott S., Stearns T.;
RT   "Proteomic analysis of mammalian sperm cells identifies new components of
RT   the centrosome.";
RL   J. Cell Sci. 127:4128-4133(2014).
CC   -!- FUNCTION: Component of centriolar satellites contributing to primary
CC       cilium formation. {ECO:0000250|UniProtKB:Q9H0I3}.
CC   -!- SUBUNIT: Interacts with HAP1 AND PCM1. {ECO:0000250|UniProtKB:Q9H0I3}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome, centriole {ECO:0000269|PubMed:25074808}. Cytoplasm,
CC       cytoskeleton, microtubule organizing center, centrosome, centriolar
CC       satellite {ECO:0000250|UniProtKB:Q9H0I3}. Note=Colocalized with HAP1 at
CC       centriolar satellites. Centriolar satellite localization requires PCM1.
CC       {ECO:0000250|UniProtKB:Q9H0I3}.
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DR   EMBL; BC102661; AAI02662.1; -; mRNA.
DR   RefSeq; NP_001069378.1; NM_001075910.2.
DR   AlphaFoldDB; Q3SZX9; -.
DR   SMR; Q3SZX9; -.
DR   STRING; 9913.ENSBTAP00000018801; -.
DR   PaxDb; Q3SZX9; -.
DR   PRIDE; Q3SZX9; -.
DR   GeneID; 528348; -.
DR   KEGG; bta:528348; -.
DR   CTD; 29070; -.
DR   eggNOG; ENOG502QU7J; Eukaryota.
DR   HOGENOM; CLU_046867_1_0_1; -.
DR   InParanoid; Q3SZX9; -.
DR   OrthoDB; 972324at2759; -.
DR   TreeFam; TF328830; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0034451; C:centriolar satellite; ISS:UniProtKB.
DR   GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR   GO; GO:0036064; C:ciliary basal body; IBA:GO_Central.
DR   GO; GO:0032991; C:protein-containing complex; ISS:UniProtKB.
DR   GO; GO:0060271; P:cilium assembly; ISS:UniProtKB.
DR   InterPro; IPR025254; DUF4201.
DR   Pfam; PF13870; DUF4201; 1.
PE   1: Evidence at protein level;
KW   Cilium biogenesis/degradation; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Reference proteome.
FT   CHAIN           1..391
FT                   /note="Coiled-coil domain-containing protein 113"
FT                   /id="PRO_0000279398"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          95..243
FT                   /evidence="ECO:0000255"
FT   COILED          294..369
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   391 AA;  45869 MW;  BB62FA52DB798334 CRC64;
     MTDDDSETSA SETQAQEESD LPVFQLCGLV EELSYGNSAL KTETEMFEKY YNKLELKDQR
     PPRLSEIKIT GAEIAQLRSR RKSKSRMGME RVMGLSVDQK LELVQKELED TKDEIRHMRA
     NAERDLQHHE AIIEEAEIRW TEVQKEVHDF EKDILKTISK KKGSILATQK VMKYIEDMNR
     RRDNMKDKLR LKNVSLKVQR KKLLLQLRQK EEVGEALHDV DFQQLKIENA QFLETIEARN
     QELIQMKLAS GNTLQILNAY KRSSLLKTSR VVILQSKLHH AMQMSLNLTK EFLLRKELLE
     KIEKETLQAE EDRAKALALN KQLRKQLSEF RAPQVMIYIW EKIRNGDLEK TIRMWERKVE
     IAEMSLKGYR KAWNKMKTTN EQLQAISGPG K