ID   YXBF_BACSU              Reviewed;         380 AA.
AC   P46330;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YxbF;
GN   Name=yxbF; Synonyms=E3A, yxaT; OrderedLocusNames=BSU39850;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / BGSC1A1;
RX   PubMed=7584049; DOI=10.1093/dnares/2.2.61;
RA   Yoshida K., Seki S., Fujimura M., Miwa Y., Fujita Y.;
RT   "Cloning and sequencing of a 36-kb region of the Bacillus subtilis genome
RT   between the gnt and iol operons.";
RL   DNA Res. 2:61-69(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   REVIEW, AND GENE FAMILY.
RX   PubMed=15944459; DOI=10.1128/mmbr.69.2.326-356.2005;
RA   Ramos J.L., Martinez-Bueno M., Molina-Henares A.J., Teran W., Watanabe K.,
RA   Zhang X., Gallegos M.T., Brennan R., Tobes R.;
RT   "The TetR family of transcriptional repressors.";
RL   Microbiol. Mol. Biol. Rev. 69:326-356(2005).
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DR   EMBL; AB005554; BAA21600.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB16021.1; -; Genomic_DNA.
DR   PIR; A70073; A70073.
DR   RefSeq; NP_391864.1; NC_000964.3.
DR   RefSeq; WP_003243187.1; NZ_JNCM01000034.1.
DR   AlphaFoldDB; P46330; -.
DR   SMR; P46330; -.
DR   STRING; 224308.BSU39850; -.
DR   PaxDb; P46330; -.
DR   PRIDE; P46330; -.
DR   EnsemblBacteria; CAB16021; CAB16021; BSU_39850.
DR   GeneID; 937637; -.
DR   KEGG; bsu:BSU39850; -.
DR   PATRIC; fig|224308.179.peg.4311; -.
DR   eggNOG; COG1309; Bacteria.
DR   InParanoid; P46330; -.
DR   OMA; YDHYANK; -.
DR   BioCyc; BSUB:BSU39850-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   Pfam; PF00440; TetR_N; 2.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   PROSITE; PS50977; HTH_TETR_2; 2.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Repeat; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..380
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YxbF"
FT                   /id="PRO_0000070656"
FT   DOMAIN          3..63
FT                   /note="HTH tetR-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT   DOMAIN          201..262
FT                   /note="HTH tetR-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT   DNA_BIND        225..244
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   380 AA;  44283 MW;  5822F267A3FB19BC CRC64;
     MPESAEAQVK EALLALLKDR DIQHITMKEI AEKAKVSRGS LYLYYEDKFS IIEDVIEDMK
     EGLGKALFDA FSHMDTLHLN KKRQTVHPTL SFVHEHRSFF SVMMNRGHFH RFFKDVFQQD
     VLLAPIHVNL TPIERDIYGH YRALYTYAII LYWLNEDAAA SPEAISQKVW ELVSQKRFYW
     LFGKAVPGER EKEKQIDRRV VRTREALQKA FLDVLAEKQD YAGITISDIT RKSNIRRATF
     YDHYANKEEL LQTMIQRSCA EIIDHLTIAS SPNEFSLKEA EKALAILLSA LSNMPIVHFL
     NREWGVPHVI PDMFKALESF YLHQQTDIHA EKKLYAHYVS AMIIGLLLYR LDEGKAHPPE
     VLAREFLQFL DVKKYKVVLL