ID   YXBG_BACSU              Reviewed;         273 AA.
AC   P46331;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   29-AUG-2003, sequence version 2.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Uncharacterized oxidoreductase YxbG;
DE            EC=1.-.-.-;
GN   Name=yxbG; Synonyms=E3BR, yxaU; OrderedLocusNames=BSU39840;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / BGSC1A1;
RX   PubMed=7584049; DOI=10.1093/dnares/2.2.61;
RA   Yoshida K., Seki S., Fujimura M., Miwa Y., Fujita Y.;
RT   "Cloning and sequencing of a 36-kb region of the Bacillus subtilis genome
RT   between the gnt and iol operons.";
RL   DNA Res. 2:61-69(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA21601.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AB005554; BAA21601.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AL009126; CAB16020.2; -; Genomic_DNA.
DR   PIR; B70073; B70073.
DR   RefSeq; NP_391863.2; NC_000964.3.
DR   RefSeq; WP_003244072.1; NZ_JNCM01000034.1.
DR   AlphaFoldDB; P46331; -.
DR   SMR; P46331; -.
DR   STRING; 224308.BSU39840; -.
DR   PaxDb; P46331; -.
DR   PRIDE; P46331; -.
DR   EnsemblBacteria; CAB16020; CAB16020; BSU_39840.
DR   GeneID; 937642; -.
DR   KEGG; bsu:BSU39840; -.
DR   PATRIC; fig|224308.179.peg.4310; -.
DR   eggNOG; COG1028; Bacteria.
DR   InParanoid; P46331; -.
DR   OMA; ICPGIIE; -.
DR   PhylomeDB; P46331; -.
DR   BioCyc; BSUB:BSU39840-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   NAD; Oxidoreductase; Reference proteome.
FT   CHAIN           1..273
FT                   /note="Uncharacterized oxidoreductase YxbG"
FT                   /id="PRO_0000054852"
FT   ACT_SITE        155
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         10..34
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   BINDING         142
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   273 AA;  29433 MW;  03DB87F060DC46F7 CRC64;
     MGRLENKTAV ITGAATGIGQ ATAEVFANEG ARVIIGDINK DQMEETVDAI RKNGGQAESF
     HLDVSDENSV KAFADQIKDA CGTIDILFNN AGVDQEGGKV HEYPVDLFDR IIAVDLRGTF
     LCSKYLIPLM LENGGSIINT SSMSGRAADL DRSGYNAAKG GITNLTKAMA IDYARNGIRV
     NSISPGTIET PLIDKLAGTK EQEMGEQFRE ANKWITPLGR LGQPKEMATV ALFLASDDSS
     YVTGEDITAD GGIMAYTWPG KMLIEEKWKE ETK