ID   YXEK_CAEEL              Reviewed;         313 AA.
AC   Q93761;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Uncharacterized oxidoreductase F53C11.3;
DE            EC=1.-.-.-;
GN   ORFNames=F53C11.3;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. 2,4-dienoyl-CoA reductase subfamily. {ECO:0000305}.
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DR   EMBL; Z79756; CAB02118.1; -; Genomic_DNA.
DR   PIR; T22556; T22556.
DR   RefSeq; NP_506413.1; NM_074012.4.
DR   AlphaFoldDB; Q93761; -.
DR   SMR; Q93761; -.
DR   BioGRID; 44886; 3.
DR   STRING; 6239.F53C11.3; -.
DR   EPD; Q93761; -.
DR   PaxDb; Q93761; -.
DR   PeptideAtlas; Q93761; -.
DR   EnsemblMetazoa; F53C11.3.1; F53C11.3.1; WBGene00009973.
DR   GeneID; 179872; -.
DR   KEGG; cel:CELE_F53C11.3; -.
DR   UCSC; F53C11.3; c. elegans.
DR   CTD; 179872; -.
DR   WormBase; F53C11.3; CE10908; WBGene00009973; -.
DR   eggNOG; KOG0725; Eukaryota.
DR   GeneTree; ENSGT00940000153801; -.
DR   HOGENOM; CLU_010194_1_2_1; -.
DR   InParanoid; Q93761; -.
DR   OMA; TIAMDGG; -.
DR   OrthoDB; 1105725at2759; -.
DR   PhylomeDB; Q93761; -.
DR   PRO; PR:Q93761; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00009973; Expressed in larva and 4 other tissues.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IBA:GO_Central.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IBA:GO_Central.
DR   GO; GO:0045087; P:innate immune response; IMP:WormBase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   NADP; Oxidoreductase; Reference proteome.
FT   CHAIN           1..313
FT                   /note="Uncharacterized oxidoreductase F53C11.3"
FT                   /id="PRO_0000054877"
FT   BINDING         29..61
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   313 AA;  33389 MW;  171F8E01E66AF370 CRC64;
     MAHCLHPEKF FPVVKSVALP PGSLNGKVAL VTGGGTGLGK AIATTFAHLG ASVAIAARRL
     DVLEKTADEI RSSTGGVCEP FQMDVKDPAK VAKAFDAVEK KLGHTPDILI NNAAGNFIMA
     TERLSPNAYG TIIDIVLKGT LHVTTELGRR CIQQKRGASV LSITTLYAQS GAPFVVPSAV
     SKAGVENMTK SLASEWAKHG LRFNAIAPGP IPTEGAFGRL FAGELKDSGD AMKASVPVGR
     LGHPEEIANL AAFMSSDFMS WMNGAIIDFD GGQQHIHHGS HMGQFLHEWD NEKWEETENL
     IRGRTGKEKK SKL