ID   YXEO_BACSU              Reviewed;         249 AA.
AC   P54954;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 138.
DE   RecName: Full=Probable amino-acid import ATP-binding protein YxeO;
DE            EC=7.4.2.-;
GN   Name=yxeO; OrderedLocusNames=BSU39480; ORFNames=LP9G;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / BGSC1A1;
RX   PubMed=8867804; DOI=10.1093/dnares/2.6.295;
RA   Yoshida K., Fujimyra M., Yanai N., Fujita Y.;
RT   "Cloning and sequencing of a 23-kb region of the Bacillus subtilis genome
RT   between the iol and hut operons.";
RL   DNA Res. 2:295-301(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   INDUCTION.
RC   STRAIN=168;
RX   PubMed=12193636; DOI=10.1128/jb.184.18.5179-5186.2002;
RA   Auger S., Danchin A., Martin-Verstraete I.;
RT   "Global expression profile of Bacillus subtilis grown in the presence of
RT   sulfate or methionine.";
RL   J. Bacteriol. 184:5179-5186(2002).
RN   [4]
RP   PROBABLE FUNCTION IN S-METHYLCYSTEINE TRANSPORT.
RC   STRAIN=168;
RX   PubMed=15262924; DOI=10.1128/jb.186.15.4875-4884.2004;
RA   Burguiere P., Auger S., Hullo M.-F., Danchin A., Martin-Verstraete I.;
RT   "Three different systems participate in L-cystine uptake in Bacillus
RT   subtilis.";
RL   J. Bacteriol. 186:4875-4884(2004).
CC   -!- FUNCTION: Probably part of the ABC transporter complex YxeMNO that
CC       could be involved in amino-acid import. May transport S-methylcysteine.
CC       Responsible for energy coupling to the transport system (Probable).
CC       {ECO:0000305}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (YxeO),
CC       two transmembrane proteins (YxeN) and a solute-binding protein (YxeM).
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Peripheral membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: More strongly expressed in the presence of methionine than
CC       in the presence of sulfate. {ECO:0000269|PubMed:12193636}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; D45912; BAA08331.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15984.1; -; Genomic_DNA.
DR   PIR; A70076; A70076.
DR   RefSeq; NP_391827.1; NC_000964.3.
DR   RefSeq; WP_003243284.1; NZ_JNCM01000034.1.
DR   AlphaFoldDB; P54954; -.
DR   SMR; P54954; -.
DR   STRING; 224308.BSU39480; -.
DR   PaxDb; P54954; -.
DR   PRIDE; P54954; -.
DR   EnsemblBacteria; CAB15984; CAB15984; BSU_39480.
DR   GeneID; 937555; -.
DR   KEGG; bsu:BSU39480; -.
DR   PATRIC; fig|224308.179.peg.4273; -.
DR   eggNOG; COG1126; Bacteria.
DR   InParanoid; P54954; -.
DR   OMA; PEVMFFD; -.
DR   PhylomeDB; P54954; -.
DR   BioCyc; BSUB:BSU39480-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015424; F:ABC-type amino acid transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR030679; ABC_ATPase_HisP-typ.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   PIRSF; PIRSF039085; ABC_ATPase_HisP; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   1: Evidence at protein level;
KW   Amino-acid transport; ATP-binding; Cell membrane; Membrane;
KW   Nucleotide-binding; Reference proteome; Translocase; Transport.
FT   CHAIN           1..249
FT                   /note="Probable amino-acid import ATP-binding protein YxeO"
FT                   /id="PRO_0000093147"
FT   DOMAIN          2..239
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         34..41
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   249 AA;  27742 MW;  A63886EDE69AB80B CRC64;
     MITVKNIRKA FKDLVVLDGI DLEVKRGEVV AIIGPSGSGK STLLRCLNLL ERPDQGLIEI
     GEAKLNAEKF TRKEAHRLRQ QTAMVFQNYN LFKNKTALQN ITEALIVAQH KPRDEAKRIG
     MEILKQVGLE HKADSYPITM SGGQQQRIGI ARALAVNPHA ILLDEPTSAL DPELVTGVLQ
     VIKSIAEKQT TMIIVTHEMA FAKEVADQVI FMADGHIIEQ GTPEELFDHP KNERTKRFIK
     QVGEPAELI