ID   YXFA_LACLA              Reviewed;         295 AA.
AC   Q9CDF7;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Putative sugar uptake protein YxfA;
GN   Name=yxfA; OrderedLocusNames=LL2264; ORFNames=L140621;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GRP transporter (TC 2.A.7.5) family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE005176; AAK06362.1; -; Genomic_DNA.
DR   PIR; H86907; H86907.
DR   RefSeq; NP_268421.1; NC_002662.1.
DR   RefSeq; WP_010906424.1; NC_002662.1.
DR   AlphaFoldDB; Q9CDF7; -.
DR   STRING; 272623.L140621; -.
DR   TCDB; 2.A.7.5.3; the drug/metabolite transporter (dmt) superfamily.
DR   PaxDb; Q9CDF7; -.
DR   DNASU; 1115942; -.
DR   EnsemblBacteria; AAK06362; AAK06362; L140621.
DR   KEGG; lla:L140621; -.
DR   PATRIC; fig|272623.7.peg.2429; -.
DR   eggNOG; COG4975; Bacteria.
DR   HOGENOM; CLU_076024_0_0_9; -.
DR   OMA; QIQFIIG; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010651; Sugar_transport.
DR   PANTHER; PTHR16119; PTHR16119; 2.
DR   Pfam; PF06800; Sugar_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..295
FT                   /note="Putative sugar uptake protein YxfA"
FT                   /id="PRO_0000213652"
FT   TRANSMEM        4..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        117..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        156..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        188..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        213..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        270..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   295 AA;  32025 MW;  E787C872BBAF0DFB CRC64;
     MQGVLLALVP MFAWGSIGFV ANKFGGDAKQ QTLGMTLGAF VFALIVFLFR MPTLTWQIFL
     IGFIGGLLWA IGQFGQFNSM KYMGVSVASP LSSGSQLVIG GLIGVFAFHE WTKQIQFILG
     FIAMAVLVVG FYFSAKRDPE NAVVEEGRNY TKGLTALTYS TLGYVIYVIL FNNLAVLWFN
     VHFDTLTIIL PMSVGMIFGA LVMGRFKIKM EKYVYQNMIV GAMWGVGNIF MLMAASAAGN
     AIAFSFSQLG VIVSTIGGIL FLGEKKTKKE LVYVGIGIVL FVTGAILLAI VKSKG