YXKC_BACSU
ID YXKC_BACSU Reviewed; 180 AA.
AC P94356; Q794X5;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-JAN-2009, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Uncharacterized protein YxkC;
DE Flags: Precursor;
GN Name=yxkC; OrderedLocusNames=BSU38850;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / BGSC1A1;
RX PubMed=8969509; DOI=10.1099/13500872-142-11-3113;
RA Yoshida K., Shindo K., Sano H., Seki S., Fujimura M., Yanai N., Miwa Y.,
RA Fujita Y.;
RT "Sequencing of a 65 kb region of the Bacillus subtilis genome containing
RT the lic and cel loci, and creation of a 177 kb contig covering the gnt-
RT sacXY region.";
RL Microbiology 142:3113-3123(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP PROTEIN SEQUENCE OF 31-41, AND SUBCELLULAR LOCATION.
RC STRAIN=168;
RX PubMed=10658653; DOI=10.1099/00221287-146-1-65;
RA Hirose I., Sano K., Shioda I., Kumano M., Nakamura K., Yamane K.;
RT "Proteome analysis of Bacillus subtilis extracellular proteins: a two-
RT dimensional protein electrophoretic study.";
RL Microbiology 146:65-75(2000).
RN [4]
RP REGULATION BY TNRA.
RX PubMed=12823818; DOI=10.1046/j.1365-2958.2003.03567.x;
RA Yoshida K., Yamaguchi H., Kinehara M., Ohki Y.-H., Nakaura Y., Fujita Y.;
RT "Identification of additional TnrA-regulated genes of Bacillus subtilis
RT associated with a TnrA box.";
RL Mol. Microbiol. 49:157-165(2003).
RN [5]
RP INDUCTION BY SIGD.
RC STRAIN=168;
RX PubMed=15033535; DOI=10.1016/j.gene.2003.12.024;
RA Serizawa M., Yamamoto H., Yamaguchi H., Fujita Y., Kobayashi K.,
RA Ogasawara N., Sekiguchi J.;
RT "Systematic analysis of SigD-regulated genes in Bacillus subtilis by DNA
RT microarray and Northern blotting analyses.";
RL Gene 329:125-136(2004).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10658653}.
CC -!- INDUCTION: Transcriptionally regulated by SigD. Negatively regulated by
CC TnrA under nitrogen-limited conditions. {ECO:0000269|PubMed:15033535}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA11719.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D83026; BAA11719.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL009126; CAB15911.2; -; Genomic_DNA.
DR PIR; F70080; F70080.
DR RefSeq; NP_391764.1; NC_000964.3.
DR AlphaFoldDB; P94356; -.
DR SMR; P94356; -.
DR STRING; 224308.BSU38850; -.
DR jPOST; P94356; -.
DR PaxDb; P94356; -.
DR PRIDE; P94356; -.
DR EnsemblBacteria; CAB15911; CAB15911; BSU_38850.
DR GeneID; 937416; -.
DR KEGG; bsu:BSU38850; -.
DR eggNOG; ENOG50348S7; Bacteria.
DR OMA; AYAKGTW; -.
DR BioCyc; BSUB:BSU38850-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.1240; -; 1.
DR InterPro; IPR029051; DUF4352.
DR InterPro; IPR029050; Immunoprotect_excell_Ig-like.
DR Pfam; PF11611; DUF4352; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Reference proteome; Secreted; Signal.
FT SIGNAL 1..30
FT /evidence="ECO:0000269|PubMed:10658653"
FT CHAIN 31..180
FT /note="Uncharacterized protein YxkC"
FT /id="PRO_0000359517"
FT REGION 25..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 180 AA; 19404 MW; 74EA3E355DC099AE CRC64;
MRHKIITFIL AVVVIIIIGN MIGGGGGSEA TSKTSSSSKA ETEKTYNIGD TVKTEKTEVT
VTKVEDRDTV GTQYVEKKAS EGGTIVAVQY TIKNVSKKPI SSFSIPTVKL VDADGTSYDS
DIDASVNYAT ETKVDNSKIL SDLNPNIKVT GVKAFEVDKE AYAKGTWKLK FSNDVIVKIK
