ID   YXNA_BACSU              Reviewed;         356 AA.
AC   O32291;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 2.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Uncharacterized oxidoreductase YxnA;
DE            EC=1.-.-.-;
GN   Name=yxnA; OrderedLocusNames=BSU40000;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; AL009126; CAB16037.2; -; Genomic_DNA.
DR   PIR; E70082; E70082.
DR   RefSeq; NP_391880.2; NC_000964.3.
DR   RefSeq; WP_003244500.1; NZ_JNCM01000034.1.
DR   AlphaFoldDB; O32291; -.
DR   SMR; O32291; -.
DR   STRING; 224308.BSU40000; -.
DR   PaxDb; O32291; -.
DR   PRIDE; O32291; -.
DR   DNASU; 937698; -.
DR   EnsemblBacteria; CAB16037; CAB16037; BSU_40000.
DR   GeneID; 937698; -.
DR   KEGG; bsu:BSU40000; -.
DR   PATRIC; fig|224308.179.peg.4326; -.
DR   eggNOG; COG1028; Bacteria.
DR   InParanoid; O32291; -.
DR   OMA; FGVMAMT; -.
DR   PhylomeDB; O32291; -.
DR   BioCyc; BSUB:BSU40000-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..356
FT                   /note="Uncharacterized oxidoreductase YxnA"
FT                   /id="PRO_0000377005"
FT   ACT_SITE        181
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         37..44
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         168
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   356 AA;  39358 MW;  BAECBD7864E690A2 CRC64;
     MTIDHSVTNT EQLEQQNPAI KTKLKLKKLK DQVIVITGAS SGIGLVTARM AAEKGAKVVA
     AARNEEALKE LTDELKEKGH DAIWVKADVG KEEDVNRIAE TAISTFGRFD TWVNNAAVST
     FGHAMDVTVE DMKRMFDTNF WGPVYGTRAA VKHYTGRGVP GALINVGSLF GDRGTVIQST
     YASAKFALHG WTESIRMELE KEQAPVSVTL IHPGRIDTPY NEHAHSYLDK QPAHYRSMIY
     PPEAVAEAIL FAAEHPKRDM YIGSQAKAIA MLGALFPRLT DRLMEKIMYH SQHAERPSNP
     REESALYDAG CGMHDRGTNK GWMRSRSYYT KATKRPIVSA AVVAGLVAWA AAKRCR