ID   YXXE_BACSU              Reviewed;         102 AA.
AC   P40738; Q45660;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Protein YxxE;
DE   AltName: Full=ORF2;
GN   Name=yxxE; OrderedLocusNames=BSU39280; ORFNames=N17B;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC   3610 / NRRL NRS-744 / VKM B-501;
RX   PubMed=7883710; DOI=10.1128/jb.177.6.1527-1535.1995;
RA   Le Coq D., Lindner C., Krueger S., Steinmetz M., Stuelke J.;
RT   "New beta-glucoside (bgl) genes in Bacillus subtilis: the bglP gene product
RT   has both transport and regulatory functions similar to those of BglF, its
RT   Escherichia coli homolog.";
RL   J. Bacteriol. 177:1527-1535(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / BGSC1A1;
RX   PubMed=7704263; DOI=10.1099/13500872-141-2-337;
RA   Yoshida K., Sano H., Seki S., Oda M., Fujimura M., Fujita Y.;
RT   "Cloning and sequencing of a 29 kb region of the Bacillus subtilis genome
RT   containing the hut and wapA loci.";
RL   Microbiology 141:337-343(1995).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=8628237; DOI=10.1007/bf02172988;
RA   Beloin C., Hirschbein L., Le Hegarat F.;
RT   "Suppression of the Bgl+ phenotype of a delta hns strain of Escherichia
RT   coli by a Bacillus subtilis antiterminator binding site.";
RL   Mol. Gen. Genet. 250:761-766(1996).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [5]
RP   DISRUPTION PHENOTYPE.
RC   STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC   3610 / NRRL NRS-744 / VKM B-501;
RX   PubMed=34280190; DOI=10.1371/journal.pgen.1009682;
RA   Kobayashi K.;
RT   "Diverse LXG toxin and antitoxin systems specifically mediate intraspecies
RT   competition in Bacillus subtilis biofilms.";
RL   PLoS Genet. 17:e1009682-e1009682(2021).
CC   -!- DISRUPTION PHENOTYPE: Deletion of the yxiB-yxiC-yxiD-yxxD-yxxE operon
CC       has no visible growth phenotype, however it is out-competed by wild-
CC       type cells. {ECO:0000269|PubMed:34280190}.
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DR   EMBL; D31856; BAA06651.1; -; Genomic_DNA.
DR   EMBL; Z34526; CAA84285.1; -; Genomic_DNA.
DR   EMBL; D29985; BAA06255.1; -; Genomic_DNA.
DR   EMBL; X85408; CAA59696.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15964.1; -; Genomic_DNA.
DR   PIR; I40405; I40405.
DR   RefSeq; NP_391807.1; NC_000964.3.
DR   RefSeq; WP_003242733.1; NZ_JNCM01000034.1.
DR   AlphaFoldDB; P40738; -.
DR   SMR; P40738; -.
DR   STRING; 224308.BSU39280; -.
DR   PaxDb; P40738; -.
DR   PRIDE; P40738; -.
DR   EnsemblBacteria; CAB15964; CAB15964; BSU_39280.
DR   GeneID; 937520; -.
DR   KEGG; bsu:BSU39280; -.
DR   PATRIC; fig|224308.179.peg.4252; -.
DR   eggNOG; ENOG5033F3X; Bacteria.
DR   OMA; INKQKDP; -.
DR   BioCyc; BSUB:BSU39280-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   InterPro; IPR041129; CdiI_2.
DR   Pfam; PF18593; CdiI_2; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..102
FT                   /note="Protein YxxE"
FT                   /id="PRO_0000050044"
FT   CONFLICT        78
FT                   /note="F -> I (in Ref. 3; CAA59696)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   102 AA;  11920 MW;  64D760189C882A27 CRC64;
     MLLINKQKDP VFQFLAGTFH QDIETPDDAI QELLIEESKE YLEDAIVFLT DFIESEHSDN
     KKNDYIQSCA DGVYLPAFNL EPIDWLKNVI VQIKKSLKKF KR