YYAP_BACSU
ID YYAP_BACSU Reviewed; 188 AA.
AC P37508;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Uncharacterized protein YyaP;
GN Name=yyaP; OrderedLocusNames=BSU40760;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA Ogasawara N., Nakai S., Yoshikawa H.;
RT "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis
RT chromosome containing the replication origin.";
RL DNA Res. 1:1-14(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) IN COMPLEX WITH PHOSPHATE.
RG Joint center for structural genomics (JCSG);
RT "Crystal structure of (2636623) from Bacillus subtilis at 2.30 A
RT resolution.";
RL Submitted (MAR-2006) to the PDB data bank.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: To B.subtilis YwjB. {ECO:0000305}.
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DR EMBL; D26185; BAA05207.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB16113.1; -; Genomic_DNA.
DR PIR; S66001; S66001.
DR RefSeq; NP_391956.1; NC_000964.3.
DR RefSeq; WP_003243497.1; NZ_JNCM01000034.1.
DR PDB; 2GD9; X-ray; 2.30 A; A/B=1-188.
DR PDBsum; 2GD9; -.
DR AlphaFoldDB; P37508; -.
DR SMR; P37508; -.
DR STRING; 224308.BSU40760; -.
DR PaxDb; P37508; -.
DR PRIDE; P37508; -.
DR EnsemblBacteria; CAB16113; CAB16113; BSU_40760.
DR GeneID; 937903; -.
DR KEGG; bsu:BSU40760; -.
DR PATRIC; fig|224308.179.peg.4418; -.
DR eggNOG; COG0262; Bacteria.
DR InParanoid; P37508; -.
DR OMA; IWLYGGA; -.
DR PhylomeDB; P37508; -.
DR BioCyc; BSUB:BSU40760-MON; -.
DR EvolutionaryTrace; P37508; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008703; F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR GO; GO:0009231; P:riboflavin biosynthetic process; IBA:GO_Central.
DR Gene3D; 3.40.430.10; -; 1.
DR InterPro; IPR024072; DHFR-like_dom_sf.
DR InterPro; IPR002734; RibDG_C.
DR Pfam; PF01872; RibD_C; 1.
DR SUPFAM; SSF53597; SSF53597; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..188
FT /note="Uncharacterized protein YyaP"
FT /id="PRO_0000050056"
FT TRANSMEM 121..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT STRAND 10..16
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 20..23
FT /evidence="ECO:0007829|PDB:2GD9"
FT HELIX 40..45
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 47..53
FT /evidence="ECO:0007829|PDB:2GD9"
FT HELIX 54..60
FT /evidence="ECO:0007829|PDB:2GD9"
FT HELIX 76..82
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 83..88
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 91..93
FT /evidence="ECO:0007829|PDB:2GD9"
FT TURN 94..97
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 98..100
FT /evidence="ECO:0007829|PDB:2GD9"
FT HELIX 103..115
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 119..125
FT /evidence="ECO:0007829|PDB:2GD9"
FT HELIX 127..135
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 141..146
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 148..150
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 152..158
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 168..174
FT /evidence="ECO:0007829|PDB:2GD9"
FT STRAND 180..185
FT /evidence="ECO:0007829|PDB:2GD9"
SQ SEQUENCE 188 AA; 21737 MW; A0D450A236490DC8 CRC64;
MTNNLKQRRI ILDLAVTLDG FIEGKNGEVD WCIMDPDMGF TDFLNQIDTI LYGRKSFDLW
GQYIPKNEDP DTEKELWKLV HSKKKYVFSR TQNEIDNQAI FINDNILEEV NKLKKNPGKD
IWLYGGASLI TTFINLGLVD EFRLSIHPVV LGEGKPLFID VKQRINLKMV NTRTFSSGVV
QIVYHWNG
