ID   YYDJ_BACSU              Reviewed;         240 AA.
AC   Q45592; Q794X3;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Probable peptide export permease protein YydJ;
GN   Name=yydJ; OrderedLocusNames=BSU40140;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9205843; DOI=10.1093/dnares/4.2.155;
RA   Kasahara Y., Nakai S., Ogasawara N.;
RT   "Sequence analysis of the 36-kb region between gntZ and trnY genes of
RT   Bacillus subtilis genome.";
RL   DNA Res. 4:155-159(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   TRANSCRIPTION REGULATION, AND OPERON SUGGESTION.
RC   STRAIN=168;
RX   PubMed=15743949; DOI=10.1128/jb.187.6.2010-2019.2005;
RA   Albano M., Smits W.K., Ho L.T., Kraigher B., Mandic-Mulec I., Kuipers O.P.,
RA   Dubnau D.;
RT   "The Rok protein of Bacillus subtilis represses genes for cell surface and
RT   extracellular functions.";
RL   J. Bacteriol. 187:2010-2019(2005).
RN   [4]
RP   SUGGESTION OF FUNCTION, OPERON STRUCTURE, AND DISRUPTION PHENOTYPE.
RC   STRAIN=168;
RX   PubMed=17921301; DOI=10.1128/jb.01181-07;
RA   Butcher B.G., Lin Y.-P., Helmann J.D.;
RT   "The yydFGHIJ operon of Bacillus subtilis encodes a peptide that induces
RT   the LiaRS two-component system.";
RL   J. Bacteriol. 189:8616-8625(2007).
CC   -!- FUNCTION: Suggested to be part of an ABC transporter complex YydIJ
CC       involved in export of the modified peptide YydF. {ECO:0000305}.
CC   -!- SUBUNIT: The complex is composed of 2 ATP-binding proteins (YydI), two
CC       transmembrane proteins (YydJ). {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: Transcriptionally repressed by rok (PubMed:15743949), this
CC       was not found to be the case in another study (PubMed:17921301).
CC       {ECO:0000269|PubMed:15743949, ECO:0000269|PubMed:17921301}.
CC   -!- DISRUPTION PHENOTYPE: Up-regulates expression of the LiaRS two-
CC       component regulatory system; this effect is more pronounced on modified
CC       competence medium than on rich or sporulation medium.
CC       {ECO:0000269|PubMed:17921301}.
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DR   EMBL; D78193; BAA11272.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB16051.1; -; Genomic_DNA.
DR   PIR; H70091; H70091.
DR   RefSeq; NP_391894.1; NC_000964.3.
DR   RefSeq; WP_003243760.1; NZ_JNCM01000034.1.
DR   AlphaFoldDB; Q45592; -.
DR   SMR; Q45592; -.
DR   STRING; 224308.BSU40140; -.
DR   TCDB; 3.A.1.133.1; the atp-binding cassette (abc) superfamily.
DR   PaxDb; Q45592; -.
DR   EnsemblBacteria; CAB16051; CAB16051; BSU_40140.
DR   GeneID; 937730; -.
DR   KEGG; bsu:BSU40140; -.
DR   PATRIC; fig|224308.179.peg.4342; -.
DR   eggNOG; ENOG5033PQ0; Bacteria.
DR   OMA; STYTVFT; -.
DR   BioCyc; BSUB:BSU40140-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..240
FT                   /note="Probable peptide export permease protein YydJ"
FT                   /id="PRO_0000370199"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   240 AA;  27505 MW;  D850555F662796FF CRC64;
     MKLEFKKSIS NKVIIILGAM FVFLFLLGYF LLVGIDKVSN VTPEMFFFSS YTVATQFGLM
     LFSFVIAFFI NREYSNKNIL FYKLIGENIY TFFYKKIAVL FLECFAFITL GLLIISLMYH
     DFSHFALLLF LFSAVILQYI LIIGTISVLC PNILISIGVS IVYWMTSVIL VAISNKTFGF
     IAPFEAGNTM YPRIERVLQS DNMTLGSNDV LFIILYLVSI IIINAIVLRF SKTRWIKMGL