ID   YYDK_BACSU              Reviewed;         236 AA.
AC   Q45591;
DT   03-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2002, sequence version 2.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YydK;
GN   Name=yydK; OrderedLocusNames=BSU40130;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9205843; DOI=10.1093/dnares/4.2.155;
RA   Kasahara Y., Nakai S., Ogasawara N.;
RT   "Sequence analysis of the 36-kb region between gntZ and trnY genes of
RT   Bacillus subtilis genome.";
RL   DNA Res. 4:155-159(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA11271.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; D78193; BAA11271.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AL009126; CAB16050.1; -; Genomic_DNA.
DR   PIR; A70092; A70092.
DR   RefSeq; NP_391893.1; NC_000964.3.
DR   RefSeq; WP_003226988.1; NZ_JNCM01000034.1.
DR   PDB; 3BWG; X-ray; 2.09 A; A/B/C=1-236.
DR   PDBsum; 3BWG; -.
DR   AlphaFoldDB; Q45591; -.
DR   SMR; Q45591; -.
DR   STRING; 224308.BSU40130; -.
DR   PaxDb; Q45591; -.
DR   PRIDE; Q45591; -.
DR   DNASU; 937726; -.
DR   EnsemblBacteria; CAB16050; CAB16050; BSU_40130.
DR   GeneID; 937726; -.
DR   KEGG; bsu:BSU40130; -.
DR   PATRIC; fig|224308.179.peg.4340; -.
DR   eggNOG; COG2188; Bacteria.
DR   InParanoid; Q45591; -.
DR   OMA; FRFFRFE; -.
DR   PhylomeDB; Q45591; -.
DR   BioCyc; BSUB:BSU40130-MON; -.
DR   EvolutionaryTrace; Q45591; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IBA:GO_Central.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.1410.10; -; 1.
DR   InterPro; IPR028978; Chorismate_lyase_/UTRA_dom_sf.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR011663; UTRA.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00392; GntR; 1.
DR   Pfam; PF07702; UTRA; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SMART; SM00866; UTRA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF64288; SSF64288; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   1: Evidence at protein level;
KW   3D-structure; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..236
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YydK"
FT                   /id="PRO_0000050692"
FT   DOMAIN          1..69
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   DNA_BIND        29..48
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   HELIX           6..17
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   HELIX           29..35
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   HELIX           40..52
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   STRAND          55..59
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   TURN            60..62
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   STRAND          63..66
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   STRAND          75..78
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   HELIX           79..81
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   STRAND          92..102
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   HELIX           106..112
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   STRAND          120..129
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   STRAND          132..142
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   TURN            143..145
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   HELIX           151..154
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   HELIX           158..164
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   STRAND          170..181
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   HELIX           184..190
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   STRAND          196..207
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   STRAND          212..220
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   TURN            222..224
FT                   /evidence="ECO:0007829|PDB:3BWG"
FT   STRAND          227..231
FT                   /evidence="ECO:0007829|PDB:3BWG"
SQ   SEQUENCE   236 AA;  27279 MW;  B6877ECA5A3858DA CRC64;
     MLKYQQIATE IETYIEEHQL QQGDKLPVLE TLMAQFEVSK STITKSLELL EQKGAIFQVR
     GSGIFVRKHK RKGYISLLSN QGFKKDLEDF NVTSKVIELD VRKPTPEAAE NLNIGMDEDI
     YYVKRVRYIN GQTLCYEESY YTKSIVTYLN NEIVSHSIFH YIREGLGLKI GFSDLFLHVG
     QLNEEEAEYL GLEAGLPKLY IESIFHLTNG QPFDYSKISY NYEQSQFVVQ ANSFLL