ID   YZ73_CAEEL              Reviewed;         146 AA.
AC   Q19297;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   06-JUN-2002, sequence version 2.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Uncharacterized monothiol glutaredoxin F10D7.3;
GN   ORFNames=F10D7.3;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the glutaredoxin family. Monothiol subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FO080923; CCD67838.1; -; Genomic_DNA.
DR   PIR; T16026; T16026.
DR   RefSeq; NP_510815.2; NM_078414.5.
DR   AlphaFoldDB; Q19297; -.
DR   SMR; Q19297; -.
DR   STRING; 6239.F10D7.3; -.
DR   iPTMnet; Q19297; -.
DR   EPD; Q19297; -.
DR   PaxDb; Q19297; -.
DR   PeptideAtlas; Q19297; -.
DR   EnsemblMetazoa; F10D7.3.1; F10D7.3.1; WBGene00017340.
DR   GeneID; 181766; -.
DR   KEGG; cel:CELE_F10D7.3; -.
DR   UCSC; F10D7.3; c. elegans.
DR   CTD; 181766; -.
DR   WormBase; F10D7.3; CE29754; WBGene00017340; -.
DR   eggNOG; KOG1752; Eukaryota.
DR   GeneTree; ENSGT00940000162420; -.
DR   HOGENOM; CLU_026126_1_0_1; -.
DR   InParanoid; Q19297; -.
DR   OMA; DSTHAQF; -.
DR   OrthoDB; 1535999at2759; -.
DR   PhylomeDB; Q19297; -.
DR   PRO; PR:Q19297; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00017340; Expressed in embryo and 4 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0015038; F:glutathione disulfide oxidoreductase activity; IBA:GO_Central.
DR   GO; GO:0097573; F:glutathione oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IBA:GO_Central.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR011899; Glutaredoxin_euk/vir.
DR   InterPro; IPR014025; Glutaredoxin_subgr.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   PRINTS; PR00160; GLUTAREDOXIN.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02180; GRX_euk; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   3: Inferred from homology;
KW   2Fe-2S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT   CHAIN           1..146
FT                   /note="Uncharacterized monothiol glutaredoxin F10D7.3"
FT                   /id="PRO_0000141654"
FT   DOMAIN          34..135
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00686"
FT   BINDING         54
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT                   /ligand_note="ligand shared between dimeric partners"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   146 AA;  16611 MW;  FF55AFE418888BC1 CRC64;
     MLRILTVVLA LVTIATVHAE LSKKKEDKTL KDLEDKIVND VMTHKVMVYS KTYCPWSKRL
     KAILANYEID DMKIVELDRS NQTEEMQEIL KKYSGRTTVP QLFISGKFVG GHDETKAIEE
     KGELRPLLEK AHALFTNRVP VPDNGA