ID   Z13_BOVIN               Reviewed;         116 AA.
AC   P82292;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2001, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Spermadhesin Z13;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Sperm;
RX   PubMed=11012670; DOI=10.1046/j.1432-1327.2000.01698.x;
RA   Tedeschi G., Oungre E., Mortarino M., Negri A., Maffeo G., Ronchi S.;
RT   "Purification and primary structure of a new bovine spermadhesin.";
RL   Eur. J. Biochem. 267:6175-6179(2000).
CC   -!- FUNCTION: May be involved in the fertilization process.
CC   -!- SUBUNIT: Homodimer; disulfide-linked.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Seminal plasma.
CC   -!- SIMILARITY: Belongs to the spermadhesin family. {ECO:0000305}.
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DR   AlphaFoldDB; P82292; -.
DR   SMR; P82292; -.
DR   STRING; 9913.ENSBTAP00000010565; -.
DR   PRIDE; P82292; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR   CDD; cd00041; CUB; 1.
DR   Gene3D; 2.60.120.290; -; 1.
DR   InterPro; IPR000859; CUB_dom.
DR   InterPro; IPR035914; Sperma_CUB_dom_sf.
DR   InterPro; IPR000124; Spermadhesin.
DR   Pfam; PF00431; CUB; 1.
DR   SMART; SM00042; CUB; 1.
DR   SUPFAM; SSF49854; SSF49854; 1.
DR   PROSITE; PS01180; CUB; 1.
DR   PROSITE; PS00985; SPERMADHESIN_1; 1.
DR   PROSITE; PS00986; SPERMADHESIN_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Fertilization;
KW   Reference proteome; Secreted.
FT   CHAIN           1..116
FT                   /note="Spermadhesin Z13"
FT                   /id="PRO_0000221457"
FT   DOMAIN          14..115
FT                   /note="CUB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00059"
FT   DISULFID        14..35
FT   DISULFID        58..79
FT   DISULFID        89
FT                   /note="Interchain"
FT   VARIANT         56
FT                   /note="E -> L"
FT   VARIANT         63
FT                   /note="L -> G"
SQ   SEQUENCE   116 AA;  13383 MW;  DE0509A30F8E303A CRC64;
     DSTDGLLVKD KYLCGDLYGE EYGVIFPYLG LKTECLWTIK MDPLYRILLT VRDVHENCNK
     ESLEIIEGPP ESSNSRKICD TSHAEYTSCT NTMTVKYTRK PNHPAPDFFL IFRRVL