ID   Z385B_DANRE             Reviewed;         492 AA.
AC   Q6PBT9;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Zinc finger protein 385B;
DE   AltName: Full=Zinc finger protein 533;
GN   Name=znf385b; Synonyms=znf533;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Retina;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in p53/TP53-mediated apoptosis.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC059587; AAH59587.1; -; mRNA.
DR   AlphaFoldDB; Q6PBT9; -.
DR   STRING; 7955.ENSDARP00000059445; -.
DR   PaxDb; Q6PBT9; -.
DR   ZFIN; ZDB-GENE-030616-154; znf385b.
DR   eggNOG; ENOG502QS7G; Eukaryota.
DR   InParanoid; Q6PBT9; -.
DR   PhylomeDB; Q6PBT9; -.
DR   PRO; PR:Q6PBT9; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; ISS:UniProtKB.
DR   InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   SMART; SM00355; ZnF_C2H2; 4.
DR   SMART; SM00451; ZnF_U1; 4.
DR   SUPFAM; SSF57667; SSF57667; 4.
PE   2: Evidence at transcript level;
KW   Apoptosis; Metal-binding; Nucleus; Reference proteome; Repeat; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..492
FT                   /note="Zinc finger protein 385B"
FT                   /id="PRO_0000191814"
FT   ZN_FING         8..44
FT                   /note="Matrin-type 1"
FT   ZN_FING         143..173
FT                   /note="Matrin-type 2"
FT   ZN_FING         303..337
FT                   /note="Matrin-type 3"
FT   ZN_FING         371..401
FT                   /note="Matrin-type 4"
FT   REGION          159..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          388..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        160..177
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        178..206
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   492 AA;  52604 MW;  6119F5554B735BFF CRC64;
     MQLQQEKKKL LYSLCDVCNI QLHSAAQAQV HYNGKSHLKR VKQLNNGEVP KASASLAPTS
     LQSLSSSSSQ GSSCHSNTLP TLVRTPSLMM QSGLDMKPFM TFPVESSSPV GLFPNFNTMD
     PVQKAVINHT FGVSIPPKKK QVISCNICQL RFNSDSQAEA HYKGSKHAKK LKAQESPKNK
     QKSAVAQDSG TKTITSTSTN TTTTTTTTSS CTAVTASCSD QTEKSTEPLA AHKVPASPQA
     FVPAPVAPAV ALVPSPCKTA PVHASPPTEP TGLAVALKNT SKPAALPTAP SEPSVESEEE
     KAKKLLYCSL CKVAVNSLSQ LEAHNTGSKH KTMLEARNGA GPIKAYPRPG SKLKVQATQL
     NKGSGLQNKT FHCEICDVHV NSEIQLKQHI SSRRHKDRVA GKPTKPKYSP YNKQQRSSSS
     LAAKLALQND LVKPISPAFL PSPFSTTTVP SISLHPRPNT SIFQTASLPH SFLRAAPGPI
     RPTTGSILFA PY