ID   Z652B_XENLA             Reviewed;         602 AA.
AC   Q6INV8;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Zinc finger protein 652-B;
GN   Name=znf652-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; BC072164; AAH72164.1; -; mRNA.
DR   RefSeq; NP_001085209.1; NM_001091740.1.
DR   AlphaFoldDB; Q6INV8; -.
DR   SMR; Q6INV8; -.
DR   GeneID; 432303; -.
DR   KEGG; xla:432303; -.
DR   CTD; 432303; -.
DR   Xenbase; XB-GENE-1020916; znf652.S.
DR   OrthoDB; 1318335at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   Bgee; 432303; Expressed in internal ear and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 4.
DR   SMART; SM00355; ZnF_C2H2; 9.
DR   SUPFAM; SSF57667; SSF57667; 5.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..602
FT                   /note="Zinc finger protein 652-B"
FT                   /id="PRO_0000280432"
FT   ZN_FING         235..258
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         262..284
FT                   /note="C2H2-type 2; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         289..312
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         319..341
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         347..369
FT                   /note="C2H2-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         375..397
FT                   /note="C2H2-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         403..425
FT                   /note="C2H2-type 7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         431..453
FT                   /note="C2H2-type 8"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         459..482
FT                   /note="C2H2-type 9; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          60..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          543..575
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        80..108
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..131
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        170..205
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        209..232
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   602 AA;  68699 MW;  C45DD54800FBC97D CRC64;
     MVVDDPCLLN IPTSFYHSTN QELDLSNKTF KREVGGPYSV MMDNKIGKPH LLETDQQNFF
     QDSKPTNEVH AVKGERENSG ESEEEEDEDD DDDDDDDDDD EEGEDEDEVN YKREQIIVEV
     NLNNQTLNVS KGDKGVPKDP SQIKTSSDDE GGDSGEDDQD SHEDEENNPL PLDGQTNMQH
     GNQDQKTENS DMVGGDGTIP ANSTKEQGKG GEAPKRKKKP KSPSDKAKSE EKETLTCDKC
     PRVFNTRWYL EKHMNVTHRR MQICDKCGKK FVLESELSLH LQTDCEKNIQ CITCNKTFKK
     LWSLHEHIKI VHGYAEKKFS CEICEKKFYT MAHVRKHLVA HTKDMPFTCE TCGKSFKRSM
     SLKVHSLQHS GEKPFRCENC DERFQYKYQL RSHMSIHIGH KQFMCQWCGK DFNMKQYFDE
     HMKTHTGEKP FICEICGKSF TSRPNMKRHR RTHTGEKPYP CDVCGMRFRF SNMLKAHKEK
     CFRVTSPVGV PPALQITLNN PTLSNPSQGI SNLPNAHIPP PSPTPPLNLN ALNPLPPRPI
     PHPFSHLHLH PHSHTHHLAV PPVPHLPPPP ALFKSEALNH RGQNDDSFLR HLAEKTSAGQ
     HH