CC124_SCHPO
ID CC124_SCHPO Reviewed; 207 AA.
AC O94389;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Coiled-coil domain-containing protein 124 homolog;
GN ORFNames=SPBC29A10.12;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the CCDC124 family. {ECO:0000305}.
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DR EMBL; CU329671; CAA22440.1; -; Genomic_DNA.
DR PIR; T40067; T40067.
DR RefSeq; NP_596057.1; NM_001021968.2.
DR AlphaFoldDB; O94389; -.
DR SMR; O94389; -.
DR BioGRID; 277069; 2.
DR STRING; 4896.SPBC29A10.12.1; -.
DR iPTMnet; O94389; -.
DR MaxQB; O94389; -.
DR PaxDb; O94389; -.
DR PRIDE; O94389; -.
DR EnsemblFungi; SPBC29A10.12.1; SPBC29A10.12.1:pep; SPBC29A10.12.
DR GeneID; 2540542; -.
DR KEGG; spo:SPBC29A10.12; -.
DR PomBase; SPBC29A10.12; -.
DR VEuPathDB; FungiDB:SPBC29A10.12; -.
DR eggNOG; KOG3223; Eukaryota.
DR HOGENOM; CLU_069723_1_1_1; -.
DR InParanoid; O94389; -.
DR OMA; RHPEKRM; -.
DR PRO; PR:O94389; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; IDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; IDA:PomBase.
DR GO; GO:0003713; F:transcription coactivator activity; IDA:PomBase.
DR GO; GO:0034599; P:cellular response to oxidative stress; IMP:PomBase.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IMP:PomBase.
DR GO; GO:0006351; P:transcription, DNA-templated; IDA:PomBase.
DR InterPro; IPR010422; Ccdc124/Oxs1.
DR PANTHER; PTHR21680; PTHR21680; 2.
DR Pfam; PF06244; Ccdc124; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..207
FT /note="Coiled-coil domain-containing protein 124 homolog"
FT /id="PRO_0000339130"
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 5..71
FT /evidence="ECO:0000255"
FT COMPBIAS 1..74
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 207 AA; 24069 MW; 9EED3A90CC47DF15 CRC64;
MGNPKKRAEK AEAAKSRKQD EEKKKKDAEE DEKWSKGVKT NKKEQEAEKR KAALERKAER
ERLEKEEMES LPSKGGKGSK KAAKKNSSLD AFLNETPQTA SYSARNIDDA LDLLSLNNSS
SKDKIDRHPE RRFKAALTEY KQSRLPELRK EQPGLRLNQY EDIMYKEFQK HPDNPFNKMN
VSYNTSQDEV EQLRKARKAE LEARLRE