ID   CC124_XENTR             Reviewed;         217 AA.
AC   Q28HN4;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Coiled-coil domain-containing protein 124;
GN   Name=ccdc124; ORFNames=TTpA004i15.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Tadpole;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for proper progression of late cytokinetic stages.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with RASGEF1B. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250}. Midbody {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCDC124 family. {ECO:0000305}.
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DR   EMBL; CR760809; CAJ83215.1; -; mRNA.
DR   RefSeq; NP_001016496.1; NM_001016496.2.
DR   RefSeq; XP_012817852.1; XM_012962398.2.
DR   AlphaFoldDB; Q28HN4; -.
DR   SMR; Q28HN4; -.
DR   PaxDb; Q28HN4; -.
DR   Ensembl; ENSXETT00000029677; ENSXETP00000029677; ENSXETG00000013543.
DR   GeneID; 549250; -.
DR   KEGG; xtr:549250; -.
DR   CTD; 115098; -.
DR   Xenbase; XB-GENE-1015198; ccdc124.
DR   eggNOG; KOG3223; Eukaryota.
DR   InParanoid; Q28HN4; -.
DR   OrthoDB; 1585903at2759; -.
DR   PhylomeDB; Q28HN4; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000013543; Expressed in heart and 13 other tissues.
DR   ExpressionAtlas; Q28HN4; baseline.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR   GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR010422; Ccdc124/Oxs1.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   PANTHER; PTHR21680; PTHR21680; 1.
DR   Pfam; PF06244; Ccdc124; 1.
DR   SUPFAM; SSF47095; SSF47095; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Reference proteome.
FT   CHAIN           1..217
FT                   /note="Coiled-coil domain-containing protein 124"
FT                   /id="PRO_0000263741"
FT   REGION          1..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          45..115
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        14..84
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   217 AA;  25462 MW;  F02749849F488571 CRC64;
     MPKKFQGENT KSAVARARKA EAKAVADAKR QKEIEDAYWQ DDDKHVMRKG QRKEDKEKKR
     LEQLERKKES QRLLEEEDSK MKGKPIKPAA PSKVTRAQIE ETLHREEEEK AISEKPKTHL
     EIPLEENLNR RILEEGEVEA RTVEDAIAAL SMSKELDRHP ERRMKAAFTA FEEINMPRIK
     QENPNMRLSQ LKQLLKKEWM KSPENPMNQQ HATYNAQ