Z804A_MOUSE
ID Z804A_MOUSE Reviewed; 1200 AA.
AC A2AKY4; Q8BHY7;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Zinc finger protein 804A;
GN Name=Znf804a; Synonyms=Zfp804a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-585.
RC STRAIN=C57BL/6J; TISSUE=Hippocampus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
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DR EMBL; AL772389; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL845296; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL928991; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK049881; BAC33969.1; -; mRNA.
DR CCDS; CCDS38160.1; -.
DR RefSeq; NP_780722.2; NM_175513.3.
DR AlphaFoldDB; A2AKY4; -.
DR BioGRID; 232318; 2.
DR STRING; 10090.ENSMUSP00000041941; -.
DR iPTMnet; A2AKY4; -.
DR PhosphoSitePlus; A2AKY4; -.
DR MaxQB; A2AKY4; -.
DR PaxDb; A2AKY4; -.
DR PeptideAtlas; A2AKY4; -.
DR PRIDE; A2AKY4; -.
DR ProteomicsDB; 298487; -.
DR Antibodypedia; 33997; 27 antibodies from 10 providers.
DR Ensembl; ENSMUST00000047527; ENSMUSP00000041941; ENSMUSG00000070866.
DR GeneID; 241514; -.
DR KEGG; mmu:241514; -.
DR UCSC; uc008khu.1; mouse.
DR CTD; 241514; -.
DR MGI; MGI:2442949; Zfp804a.
DR VEuPathDB; HostDB:ENSMUSG00000070866; -.
DR eggNOG; ENOG502QQR4; Eukaryota.
DR GeneTree; ENSGT00940000160909; -.
DR HOGENOM; CLU_276771_0_0_1; -.
DR InParanoid; A2AKY4; -.
DR OMA; DHRCLVL; -.
DR OrthoDB; 332880at2759; -.
DR PhylomeDB; A2AKY4; -.
DR TreeFam; TF332138; -.
DR BioGRID-ORCS; 241514; 3 hits in 70 CRISPR screens.
DR ChiTaRS; Zfp804a; mouse.
DR PRO; PR:A2AKY4; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; A2AKY4; protein.
DR Bgee; ENSMUSG00000070866; Expressed in lateral geniculate body and 91 other tissues.
DR Genevisible; A2AKY4; MM.
DR GO; GO:0030424; C:axon; ISO:MGI.
DR GO; GO:0005737; C:cytoplasm; ISO:MGI.
DR GO; GO:1901588; C:dendritic microtubule; ISO:MGI.
DR GO; GO:0043198; C:dendritic shaft; ISO:MGI.
DR GO; GO:0043197; C:dendritic spine; ISO:MGI.
DR GO; GO:0030426; C:growth cone; ISO:MGI.
DR GO; GO:0043025; C:neuronal cell body; ISO:MGI.
DR GO; GO:0005634; C:nucleus; ISO:MGI.
DR GO; GO:0005886; C:plasma membrane; ISO:MGI.
DR GO; GO:0098794; C:postsynapse; ISO:MGI.
DR GO; GO:0098793; C:presynapse; ISO:MGI.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:1902952; P:positive regulation of dendritic spine maintenance; ISO:MGI.
DR GO; GO:0010628; P:positive regulation of gene expression; ISO:MGI.
DR GO; GO:0010976; P:positive regulation of neuron projection development; ISO:MGI.
DR GO; GO:0010975; P:regulation of neuron projection development; ISO:MGI.
DR InterPro; IPR022755; Znf_C2H2_jaz.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF12171; zf-C2H2_jaz; 1.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..1200
FT /note="Zinc finger protein 804A"
FT /id="PRO_0000289141"
FT ZN_FING 57..81
FT /note="C2H2-type"
FT REGION 252..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 727..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 799..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 874..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..600
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..660
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..754
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 755..771
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..949
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1200 AA; 134850 MW; 86D80C8E15D72016 CRC64;
MECYYIVISS THLSNGHFRN IKGVFRGPLS KNGNKTLDYA EKENTIAKAL EDLKANFYCE
LCDKQYYKHQ EFDNHINSYD HAHKQRLKEL KQREFARNVA SKSRKDERKQ EKALQRLHKL
AELRKETVCA PGSGPMFKST TVTVRENLND VSQRESVDPI NNQQDLIPSE EKERDGTTAL
AETETASNCT ANNCQIGDQS QAVHRHRIGF SFAFPKKATV KLESCSAAAF SEYSDESSME
KEFSRKTRFV PSTSHLQLPP PTCELLSSEE KGNSPPPEAM CTDKATAQTE ERKITSNENN
TLLTSSFCQL QHYIPTCSEA DTCQNLAPFE DQLPMEAVIV NEDGPVSKSN PNIIEKNPTV
PNDRTSAQMT TEENITINDV TKMETRNKID HEPLTPSSTI EESIRLQKRP DLCKRQCDPF
VPVLNKLGST VLQWPSEMLA YTTTEPSISY SCNPLCFDFK STKLNNNQDK NKLTLNDLFS
EQKEDCCKGA HADCKDVPIA RVTNDETGHS KNDYPQVTTL SPVHVLSNGC DLGQNENVGQ
RYKHISCTNR QTNKYKFTRC QIKRDMLNEK YDKMRLKETR EHWFHKSRRK KKRRKLCRYH
PGKSSKEPEG SGKTERSRQR TDEARKNPRE PVLEKHPRSP ERASDLHQLP DERPKAASTH
LGEKETMNTT VNTESNDAAP GSQNCGGKNA TVVNEQAKPL VIHSVKQNLT YVRTYCCWKA
RTSRYQEDDG SLASQSNVKG PTQNQPVKRG YSSLTNDSER IHRKRRQHSC SYSSDESLNQ
QHHLGEYLKP LSTSLISCQP KKKRRRKRSR LHIGDGTTKM KGNSNYPMKC SSLSQPDELA
KDCIKEDINP QENVSIEKNS EQTEQTEIKG MLHPYNPLLS EPSGEGEHSV TETTPCDSSQ
TSNDLATPVN VTRDPSNSTT DNTLLEHNQR SQTTNSNEKQ TPFKVTNPER NFRHSQAKSY
ICRYELAETI PQGKTNEAST EWLCYNSGIL NTQPPLQFKE AHVSGHAFVT TEQILAPLPL
PEQALLIPLE NHDKLKHLPC EVYQHIIQPN MLTNKVKFTF PPPPLPPPST PVQPLPLQRP
FCSTSVTTIH HTVLQHHAAA AAAAAAAAAA GTFKVLQPHQ QFLPQVPALA RTSIPQISVG
TVGPRLCPGG QPALVASPQM PIIPASVLHP SPLAFPPLPH SFFPSLLSPH PTVIPLQPLF
