ID   ZAPA_ACTP2              Reviewed;         106 AA.
AC   A3MYI2;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Cell division protein ZapA;
DE   AltName: Full=Z ring-associated protein ZapA;
GN   Name=zapA; OrderedLocusNames=APL_0110;
OS   Actinobacillus pleuropneumoniae serotype 5b (strain L20).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=416269;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L20;
RX   PubMed=18065534; DOI=10.1128/jb.01845-07;
RA   Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M.,
RA   Nash J.H.E.;
RT   "The complete genome sequence of Actinobacillus pleuropneumoniae L20
RT   (serotype 5b).";
RL   J. Bacteriol. 190:1495-1496(2008).
CC   -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC       GTPase activity, therefore promoting FtsZ assembly into bundles of
CC       protofilaments necessary for the formation of the division Z ring. It
CC       is recruited early at mid-cell but it is not essential for cell
CC       division (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. Interacts with FtsZ (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes at mid-
CC       cell. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZapA family. Type 1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CP000569; ABN73218.1; -; Genomic_DNA.
DR   RefSeq; WP_005600115.1; NC_009053.1.
DR   AlphaFoldDB; A3MYI2; -.
DR   SMR; A3MYI2; -.
DR   STRING; 416269.APL_0110; -.
DR   EnsemblBacteria; ABN73218; ABN73218; APL_0110.
DR   KEGG; apl:APL_0110; -.
DR   eggNOG; COG3027; Bacteria.
DR   HOGENOM; CLU_116623_3_0_6; -.
DR   OMA; LESCIHQ; -.
DR   Proteomes; UP000001432; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.160.880; -; 1.
DR   InterPro; IPR007838; Cell_div_ZapA-like.
DR   InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR   InterPro; IPR042233; Cell_div_ZapA_N.
DR   PANTHER; PTHR34981; PTHR34981; 1.
DR   Pfam; PF05164; ZapA; 1.
DR   SUPFAM; SSF102829; SSF102829; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Coiled coil; Cytoplasm; Reference proteome;
KW   Septation.
FT   CHAIN           1..106
FT                   /note="Cell division protein ZapA"
FT                   /id="PRO_0000346118"
FT   COILED          22..81
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   106 AA;  11798 MW;  7117E85811F2B11E CRC64;
     MSANYIEVQI FGQVLRLHCP PDQQENLLAS AQRLEERVAL LKDQSGIIQL EKVLAIVALN
     LNYELEQEKQ KNANNKAVLE SCIHQLDNSL SKLLSGSSVA INQESV