ZAPA_ACTPJ
ID ZAPA_ACTPJ Reviewed; 106 AA.
AC B0BS15;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 1.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Cell division protein ZapA;
DE AltName: Full=Z ring-associated protein ZapA;
GN Name=zapA; OrderedLocusNames=APJL_0111;
OS Actinobacillus pleuropneumoniae serotype 3 (strain JL03).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Actinobacillus.
OX NCBI_TaxID=434271;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JL03;
RX PubMed=18197260; DOI=10.1371/journal.pone.0001450;
RA Xu Z., Zhou Y., Li L., Zhou R., Xiao S., Wan Y., Zhang S., Wang K., Li W.,
RA Li L., Jin H., Kang M., Dalai B., Li T., Liu L., Cheng Y., Zhang L., Xu T.,
RA Zheng H., Pu S., Wang B., Gu W., Zhang X.L., Zhu G.-F., Wang S.,
RA Zhao G.-P., Chen H.;
RT "Genome biology of Actinobacillus pleuropneumoniae JL03, an isolate of
RT serotype 3 prevalent in China.";
RL PLoS ONE 3:E1450-E1450(2008).
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes at mid-
CC cell. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ZapA family. Type 1 subfamily.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000687; ABY68715.1; -; Genomic_DNA.
DR RefSeq; WP_012262701.1; NC_010278.1.
DR AlphaFoldDB; B0BS15; -.
DR SMR; B0BS15; -.
DR EnsemblBacteria; ABY68715; ABY68715; APJL_0111.
DR KEGG; apj:APJL_0111; -.
DR HOGENOM; CLU_116623_3_0_6; -.
DR OMA; LESCIHQ; -.
DR OrthoDB; 1802106at2; -.
DR Proteomes; UP000008547; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.880; -; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR InterPro; IPR042233; Cell_div_ZapA_N.
DR PANTHER; PTHR34981; PTHR34981; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; SSF102829; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Coiled coil; Cytoplasm; Septation.
FT CHAIN 1..106
FT /note="Cell division protein ZapA"
FT /id="PRO_0000346119"
FT COILED 22..81
FT /evidence="ECO:0000255"
SQ SEQUENCE 106 AA; 11863 MW; 711D42480158A104 CRC64;
MSANYIEVQI FGQVLRFHCP PDQQENLLAS AQRLEERVAL LKDQSGIIQL EKVLTIVALN
LNYELEQEKQ KNANNKAVLE SCIHQLDNSL SKLLSGSSVA INQESV