ZAPA_ACTSZ
ID ZAPA_ACTSZ Reviewed; 107 AA.
AC A6VM35;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 25-MAY-2022, entry version 65.
DE RecName: Full=Cell division protein ZapA;
DE AltName: Full=Z ring-associated protein ZapA;
GN Name=zapA; OrderedLocusNames=Asuc_0659;
OS Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 /
OS 130Z).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Actinobacillus.
OX NCBI_TaxID=339671;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z;
RX PubMed=21118570; DOI=10.1186/1471-2164-11-680;
RA McKinlay J.B., Laivenieks M., Schindler B.D., McKinlay A.A.,
RA Siddaramappa S., Challacombe J.F., Lowry S.R., Clum A., Lapidus A.L.,
RA Burkhart K.B., Harkins V., Vieille C.;
RT "A genomic perspective on the potential of Actinobacillus succinogenes for
RT industrial succinate production.";
RL BMC Genomics 11:680-680(2010).
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes at mid-
CC cell. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ZapA family. Type 1 subfamily.
CC {ECO:0000305}.
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DR EMBL; CP000746; ABR74032.1; -; Genomic_DNA.
DR RefSeq; WP_012072412.1; NC_009655.1.
DR AlphaFoldDB; A6VM35; -.
DR SMR; A6VM35; -.
DR STRING; 339671.Asuc_0659; -.
DR EnsemblBacteria; ABR74032; ABR74032; Asuc_0659.
DR KEGG; asu:Asuc_0659; -.
DR eggNOG; COG3027; Bacteria.
DR HOGENOM; CLU_116623_3_0_6; -.
DR OMA; LESCIHQ; -.
DR OrthoDB; 1802106at2; -.
DR Proteomes; UP000001114; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.880; -; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR InterPro; IPR042233; Cell_div_ZapA_N.
DR PANTHER; PTHR34981; PTHR34981; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; SSF102829; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Coiled coil; Cytoplasm; Reference proteome;
KW Septation.
FT CHAIN 1..107
FT /note="Cell division protein ZapA"
FT /id="PRO_0000346120"
FT COILED 21..99
FT /evidence="ECO:0000255"
SQ SEQUENCE 107 AA; 12334 MW; C965E8E7D1063AB0 CRC64;
MALKPIELNF LGQVVRLNAP EEQHNDLRDA AKELDKRVSE MKDRMQTVQV ERAVHVVALN
LCFELLLEKQ KTKSTEQILQ NQIQQLSHSL ENIAARSTNQ QPAYEIQ