ID   ZAPA_ALKCK              Reviewed;          78 AA.
AC   Q5WEJ7;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Cell division protein ZapA;
DE   AltName: Full=Z ring-associated protein ZapA;
GN   Name=zapA; OrderedLocusNames=ABC2678;
OS   Alkalihalobacillus clausii (strain KSM-K16) (Bacillus clausii).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX   NCBI_TaxID=66692;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSM-K16;
RA   Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y.,
RA   Kawai S., Ito S., Horikoshi K.;
RT   "The complete genome sequence of the alkaliphilic Bacillus clausii KSM-
RT   K16.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC       GTPase activity, therefore promoting FtsZ assembly into bundles of
CC       protofilaments necessary for the formation of the division Z ring. It
CC       is recruited early at mid-cell but it is not essential for cell
CC       division (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. Interacts with FtsZ (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes at mid-
CC       cell. In sporulating cells, localizes near the cell poles (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZapA family. Type 2 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AP006627; BAD65213.1; -; Genomic_DNA.
DR   RefSeq; WP_011247521.1; NC_006582.1.
DR   AlphaFoldDB; Q5WEJ7; -.
DR   SMR; Q5WEJ7; -.
DR   STRING; 66692.ABC2678; -.
DR   PRIDE; Q5WEJ7; -.
DR   EnsemblBacteria; BAD65213; BAD65213; ABC2678.
DR   KEGG; bcl:ABC2678; -.
DR   eggNOG; COG3027; Bacteria.
DR   HOGENOM; CLU_116623_4_0_9; -.
DR   OMA; KMHEFSE; -.
DR   OrthoDB; 1802106at2; -.
DR   Proteomes; UP000001168; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR007838; Cell_div_ZapA-like.
DR   InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR   PANTHER; PTHR34981; PTHR34981; 1.
DR   Pfam; PF05164; ZapA; 1.
DR   SUPFAM; SSF102829; SSF102829; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome; Septation.
FT   CHAIN           1..78
FT                   /note="Cell division protein ZapA"
FT                   /id="PRO_0000345686"
SQ   SEQUENCE   78 AA;  9089 MW;  F83552879D1CBE1C CRC64;
     MEKNNNKKRA TVRIQGQTYK VVSSEEPAHV KEVASYMNKK MEELKKRNPY LDSTKLAVLT
     ALNIADEYLK LKRQYEGE