ZAPA_ALKHC
ID ZAPA_ALKHC Reviewed; 91 AA.
AC Q9K897;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=Cell division protein ZapA;
DE AltName: Full=Z ring-associated protein ZapA;
GN Name=zapA; OrderedLocusNames=BH3109;
OS Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS / JCM 9153 / C-125) (Bacillus halodurans).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX NCBI_TaxID=272558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT and genomic sequence comparison with Bacillus subtilis.";
RL Nucleic Acids Res. 28:4317-4331(2000).
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes at mid-
CC cell. In sporulating cells, localizes near the cell poles (By
CC similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ZapA family. Type 2 subfamily.
CC {ECO:0000305}.
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DR EMBL; BA000004; BAB06828.1; -; Genomic_DNA.
DR PIR; E84038; E84038.
DR RefSeq; WP_010899253.1; NC_002570.2.
DR AlphaFoldDB; Q9K897; -.
DR SMR; Q9K897; -.
DR STRING; 272558.10175731; -.
DR EnsemblBacteria; BAB06828; BAB06828; BAB06828.
DR KEGG; bha:BH3109; -.
DR eggNOG; COG3027; Bacteria.
DR HOGENOM; CLU_116623_4_0_9; -.
DR OMA; KMHEFSE; -.
DR OrthoDB; 1802106at2; -.
DR Proteomes; UP000001258; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR PANTHER; PTHR34981; PTHR34981; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; SSF102829; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Coiled coil; Cytoplasm; Reference proteome;
KW Septation.
FT CHAIN 1..91
FT /note="Cell division protein ZapA"
FT /id="PRO_0000345682"
FT COILED 62..82
FT /evidence="ECO:0000255"
SQ SEQUENCE 91 AA; 10736 MW; 2ABE88B4CE9F4C3C CRC64;
MKERQREKQR TTVSIYGQQY TVAGYDSPEY MKEVAAEIDA KMRELRKVNP YLDTTRLAVL
TAVNVMDDLK KLEEYIRYLE QQRLTGDEKN A