ZAPA_BACLD
ID ZAPA_BACLD Reviewed; 85 AA.
AC Q65GD9; Q62RU5;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Cell division protein ZapA {ECO:0000255|HAMAP-Rule:MF_02013};
DE AltName: Full=Z ring-associated protein ZapA {ECO:0000255|HAMAP-Rule:MF_02013};
GN Name=zapA {ECO:0000255|HAMAP-Rule:MF_02013};
GN OrderedLocusNames=BLi03008, BL00337;
OS Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 /
OS NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=279010;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375
RC / NCTC 10341 / NRRL NRS-1264 / Gibson 46;
RX PubMed=15383718; DOI=10.1159/000079829;
RA Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P.,
RA Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G.;
RT "The complete genome sequence of Bacillus licheniformis DSM13, an organism
RT with great industrial potential.";
RL J. Mol. Microbiol. Biotechnol. 7:204-211(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375
RC / NCTC 10341 / NRRL NRS-1264 / Gibson 46;
RX PubMed=15461803; DOI=10.1186/gb-2004-5-10-r77;
RA Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J.,
RA Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B.,
RA Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A.,
RA Bolotin A., Lapidus A., Galleron N., Ehrlich S.D., Berka R.M.;
RT "Complete genome sequence of the industrial bacterium Bacillus
RT licheniformis and comparisons with closely related Bacillus species.";
RL Genome Biol. 5:R77.1-R77.12(2004).
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division. {ECO:0000255|HAMAP-Rule:MF_02013}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_02013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02013}.
CC Note=Localizes at mid-cell. In sporulating cells, localizes near the
CC cell poles. {ECO:0000255|HAMAP-Rule:MF_02013}.
CC -!- SIMILARITY: Belongs to the ZapA family. Type 2 subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_02013}.
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DR EMBL; CP000002; AAU24515.2; -; Genomic_DNA.
DR EMBL; AE017333; AAU41875.1; -; Genomic_DNA.
DR RefSeq; WP_003184205.1; NC_006322.1.
DR AlphaFoldDB; Q65GD9; -.
DR SMR; Q65GD9; -.
DR STRING; 279010.BL00337; -.
DR EnsemblBacteria; AAU24515; AAU24515; BL00337.
DR GeneID; 66215009; -.
DR KEGG; bld:BLi03008; -.
DR KEGG; bli:BL00337; -.
DR eggNOG; COG3027; Bacteria.
DR HOGENOM; CLU_116623_4_0_9; -.
DR OMA; KMHEFSE; -.
DR OrthoDB; 1802106at2; -.
DR BioCyc; BLIC279010:BLI_RS14880-MON; -.
DR Proteomes; UP000000606; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR HAMAP; MF_02013; ZapA_type2; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR InterPro; IPR023688; Cell_div_ZapA_firmicutes.
DR PANTHER; PTHR34981; PTHR34981; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; SSF102829; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Coiled coil; Cytoplasm; Reference proteome;
KW Septation.
FT CHAIN 1..85
FT /note="Cell division protein ZapA"
FT /id="PRO_0000345684"
FT COILED 60..85
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02013"
SQ SEQUENCE 85 AA; 9788 MW; 3FE09D3EDD2351AB CRC64;
MSDGQKTKTT VDIYGQQFTI VGDESKSHMR HVASIVDDKM REINEKNPYL DINKLAVLTA
VNVVHDYLKL KEELERLKGQ IKEKD