ID   ZAPA_BACP2              Reviewed;          85 AA.
AC   A8FG14;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Cell division protein ZapA {ECO:0000255|HAMAP-Rule:MF_02013};
DE   AltName: Full=Z ring-associated protein ZapA {ECO:0000255|HAMAP-Rule:MF_02013};
GN   Name=zapA {ECO:0000255|HAMAP-Rule:MF_02013}; OrderedLocusNames=BPUM_2519;
OS   Bacillus pumilus (strain SAFR-032).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=315750;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SAFR-032;
RX   PubMed=17895969; DOI=10.1371/journal.pone.0000928;
RA   Gioia J., Yerrapragada S., Qin X., Jiang H., Igboeli O.C., Muzny D.,
RA   Dugan-Rocha S., Ding Y., Hawes A., Liu W., Perez L., Kovar C., Dinh H.,
RA   Lee S., Nazareth L., Blyth P., Holder M., Buhay C., Tirumalai M.R., Liu Y.,
RA   Dasgupta I., Bokhetache L., Fujita M., Karouia F., Eswara Moorthy P.,
RA   Siefert J., Uzman A., Buzumbo P., Verma A., Zwiya H., McWilliams B.D.,
RA   Olowu A., Clinkenbeard K.D., Newcombe D., Golebiewski L., Petrosino J.F.,
RA   Nicholson W.L., Fox G.E., Venkateswaran K., Highlander S.K.,
RA   Weinstock G.M.;
RT   "Paradoxical DNA repair and peroxide resistance gene conservation in
RT   Bacillus pumilus SAFR-032.";
RL   PLoS ONE 2:E928-E928(2007).
CC   -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC       GTPase activity, therefore promoting FtsZ assembly into bundles of
CC       protofilaments necessary for the formation of the division Z ring. It
CC       is recruited early at mid-cell but it is not essential for cell
CC       division. {ECO:0000255|HAMAP-Rule:MF_02013}.
CC   -!- SUBUNIT: Homodimer. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_02013}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02013}.
CC       Note=Localizes at mid-cell. In sporulating cells, localizes near the
CC       cell poles. {ECO:0000255|HAMAP-Rule:MF_02013}.
CC   -!- SIMILARITY: Belongs to the ZapA family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_02013}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000813; ABV63181.1; -; Genomic_DNA.
DR   RefSeq; WP_012010831.1; NZ_VEIS01000006.1.
DR   AlphaFoldDB; A8FG14; -.
DR   SMR; A8FG14; -.
DR   STRING; 315750.BPUM_2519; -.
DR   EnsemblBacteria; ABV63181; ABV63181; BPUM_2519.
DR   GeneID; 61769527; -.
DR   KEGG; bpu:BPUM_2519; -.
DR   eggNOG; COG3027; Bacteria.
DR   HOGENOM; CLU_116623_4_0_9; -.
DR   OMA; KMHEFSE; -.
DR   OrthoDB; 1802106at2; -.
DR   Proteomes; UP000001355; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   HAMAP; MF_02013; ZapA_type2; 1.
DR   InterPro; IPR007838; Cell_div_ZapA-like.
DR   InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR   InterPro; IPR023688; Cell_div_ZapA_firmicutes.
DR   PANTHER; PTHR34981; PTHR34981; 1.
DR   Pfam; PF05164; ZapA; 1.
DR   SUPFAM; SSF102829; SSF102829; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Coiled coil; Cytoplasm; Reference proteome;
KW   Septation.
FT   CHAIN           1..85
FT                   /note="Cell division protein ZapA"
FT                   /id="PRO_0000345685"
FT   COILED          60..85
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02013"
SQ   SEQUENCE   85 AA;  9883 MW;  9C3F4A3CBA654510 CRC64;
     MSDGGKTKTT VEIYGQSYTI IGQETKMHMR HVASIVDDKM REINEKNPYL DINKLAVLTA
     VNVVHDYLKL KEQYEKLEIQ LKEKE