ID   ZAPA_HAEIN              Reviewed;         100 AA.
AC   P44062;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Cell division protein ZapA;
DE   AltName: Full=Z ring-associated protein ZapA;
GN   Name=zapA; OrderedLocusNames=HI_0857;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC       GTPase activity, therefore promoting FtsZ assembly into bundles of
CC       protofilaments necessary for the formation of the division Z ring. It
CC       is recruited early at mid-cell but it is not essential for cell
CC       division (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. Interacts with FtsZ (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes at mid-
CC       cell. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZapA family. Type 1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; L42023; AAC22516.1; -; Genomic_DNA.
DR   PIR; H64014; H64014.
DR   RefSeq; NP_439017.1; NC_000907.1.
DR   RefSeq; WP_005651366.1; NC_000907.1.
DR   AlphaFoldDB; P44062; -.
DR   SMR; P44062; -.
DR   STRING; 71421.HI_0857; -.
DR   EnsemblBacteria; AAC22516; AAC22516; HI_0857.
DR   KEGG; hin:HI_0857; -.
DR   PATRIC; fig|71421.8.peg.898; -.
DR   eggNOG; COG3027; Bacteria.
DR   HOGENOM; CLU_116623_3_0_6; -.
DR   OMA; LESCIHQ; -.
DR   PhylomeDB; P44062; -.
DR   BioCyc; HINF71421:G1GJ1-897-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR   GO; GO:0030428; C:cell septum; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0000917; P:division septum assembly; IBA:GO_Central.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IBA:GO_Central.
DR   GO; GO:0000921; P:septin ring assembly; IBA:GO_Central.
DR   Gene3D; 3.30.160.880; -; 1.
DR   InterPro; IPR007838; Cell_div_ZapA-like.
DR   InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR   InterPro; IPR042233; Cell_div_ZapA_N.
DR   PANTHER; PTHR34981; PTHR34981; 1.
DR   Pfam; PF05164; ZapA; 1.
DR   SUPFAM; SSF102829; SSF102829; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Coiled coil; Cytoplasm; Reference proteome;
KW   Septation.
FT   CHAIN           1..100
FT                   /note="Cell division protein ZapA"
FT                   /id="PRO_0000169354"
FT   COILED          21..45
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   100 AA;  11422 MW;  756D6F5E108C7DAD CRC64;
     MSLKLVEILV LGQVLRLNVP IEQEELLRQA ARNLDILVSE MKEKTGLIQL DRVLSIVALN
     LSFELSQEKN KTAKIEEVLR TGIQQLDHSL ENIRVTKEPH