ID   ZAPA_HISS2              Reviewed;          99 AA.
AC   B0UTH6;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Cell division protein ZapA;
DE   AltName: Full=Z ring-associated protein ZapA;
GN   Name=zapA; OrderedLocusNames=HSM_1095;
OS   Histophilus somni (strain 2336) (Haemophilus somnus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=228400;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2336;
RG   US DOE Joint Genome Institute;
RA   Siddaramappa S., Duncan A.J., Challacombe J.F., Rainey D., Gillaspy A.F.,
RA   Carson M., Gipson J., Gipson M., Bruce D., Detter J.C., Han C.S., Land M.,
RA   Tapia R., Thompson L.S., Orvis J., Zaitshik J., Barnes G., Brettin T.S.,
RA   Dyer D.W., Inzana T.J.;
RT   "Complete sequence of Haemophilus somnus 2336.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC       GTPase activity, therefore promoting FtsZ assembly into bundles of
CC       protofilaments necessary for the formation of the division Z ring. It
CC       is recruited early at mid-cell but it is not essential for cell
CC       division (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. Interacts with FtsZ (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes at mid-
CC       cell. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZapA family. Type 1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CP000947; ACA30812.1; -; Genomic_DNA.
DR   RefSeq; WP_011608840.1; NC_010519.1.
DR   AlphaFoldDB; B0UTH6; -.
DR   SMR; B0UTH6; -.
DR   STRING; 228400.HSM_1095; -.
DR   EnsemblBacteria; ACA30812; ACA30812; HSM_1095.
DR   GeneID; 56965097; -.
DR   KEGG; hsm:HSM_1095; -.
DR   HOGENOM; CLU_116623_3_0_6; -.
DR   OMA; NICYELH; -.
DR   OrthoDB; 1802106at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.160.880; -; 1.
DR   InterPro; IPR007838; Cell_div_ZapA-like.
DR   InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR   InterPro; IPR042233; Cell_div_ZapA_N.
DR   PANTHER; PTHR34981; PTHR34981; 1.
DR   Pfam; PF05164; ZapA; 1.
DR   SUPFAM; SSF102829; SSF102829; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Coiled coil; Cytoplasm; Septation.
FT   CHAIN           1..99
FT                   /note="Cell division protein ZapA"
FT                   /id="PRO_0000346126"
FT   COILED          76..96
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   99 AA;  11301 MW;  3F8F28EF30895D72 CRC64;
     MSKLIELSVS GQVLRLNCPP EQHDALRQAA HLLDNRVMEM RERTGILQME KILSIVALNL
     SFELMQEQQK TQTIENVINQ KIAQLEGSLE NILAQKTTF