ZAPA_SALTY
ID ZAPA_SALTY Reviewed; 109 AA.
AC Q7CPU9;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Cell division protein ZapA {ECO:0000255|HAMAP-Rule:MF_02012};
DE AltName: Full=Z ring-associated protein ZapA {ECO:0000255|HAMAP-Rule:MF_02012};
GN Name=zapA {ECO:0000255|HAMAP-Rule:MF_02012}; OrderedLocusNames=STM3060;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division. {ECO:0000255|HAMAP-Rule:MF_02012}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_02012}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02012}.
CC Note=Localizes at mid-cell. {ECO:0000255|HAMAP-Rule:MF_02012}.
CC -!- SIMILARITY: Belongs to the ZapA family. Type 1 subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_02012}.
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DR EMBL; AE006468; AAL21935.1; -; Genomic_DNA.
DR RefSeq; NP_461976.1; NC_003197.2.
DR RefSeq; WP_001276011.1; NC_003197.2.
DR AlphaFoldDB; Q7CPU9; -.
DR SMR; Q7CPU9; -.
DR STRING; 99287.STM3060; -.
DR PaxDb; Q7CPU9; -.
DR EnsemblBacteria; AAL21935; AAL21935; STM3060.
DR GeneID; 1254583; -.
DR GeneID; 66757358; -.
DR KEGG; stm:STM3060; -.
DR PATRIC; fig|99287.12.peg.3242; -.
DR HOGENOM; CLU_116623_3_0_6; -.
DR OMA; NICYELH; -.
DR PhylomeDB; Q7CPU9; -.
DR BioCyc; SENT99287:STM3060-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR GO; GO:0030428; C:cell septum; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0000917; P:division septum assembly; IBA:GO_Central.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IBA:GO_Central.
DR GO; GO:0000921; P:septin ring assembly; IBA:GO_Central.
DR Gene3D; 3.30.160.880; -; 1.
DR HAMAP; MF_02012; ZapA_type1; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR InterPro; IPR023771; Cell_div_ZapA_eubact.
DR InterPro; IPR042233; Cell_div_ZapA_N.
DR PANTHER; PTHR34981; PTHR34981; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; SSF102829; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Coiled coil; Cytoplasm; Reference proteome;
KW Septation.
FT CHAIN 1..109
FT /note="Cell division protein ZapA"
FT /id="PRO_0000345658"
FT COILED 21..97
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02012"
SQ SEQUENCE 109 AA; 12523 MW; 2677651A6E9F8C98 CRC64;
MSAQPVDIQI FGRSLRVNCP PDQRDALNQA ADDLNQRLQD LKVRTRVTNT EQLVFIAALN
ISYELTQEKA KTRDYAASME QRIRMLQQTI EQALLDQGRI TEKTGQNFE
