ZAPA_SERP5
ID ZAPA_SERP5 Reviewed; 109 AA.
AC A8GIS6;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2007, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Cell division protein ZapA {ECO:0000255|HAMAP-Rule:MF_02012};
DE AltName: Full=Z ring-associated protein ZapA {ECO:0000255|HAMAP-Rule:MF_02012};
GN Name=zapA {ECO:0000255|HAMAP-Rule:MF_02012}; OrderedLocusNames=Spro_3921;
OS Serratia proteamaculans (strain 568).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=399741;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=568;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA Vangronsveld J., van der Lelie D., Richardson P.;
RT "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division. {ECO:0000255|HAMAP-Rule:MF_02012}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_02012}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02012}.
CC Note=Localizes at mid-cell. {ECO:0000255|HAMAP-Rule:MF_02012}.
CC -!- SIMILARITY: Belongs to the ZapA family. Type 1 subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_02012}.
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DR EMBL; CP000826; ABV43016.1; -; Genomic_DNA.
DR RefSeq; WP_012146623.1; NC_009832.1.
DR AlphaFoldDB; A8GIS6; -.
DR SMR; A8GIS6; -.
DR STRING; 399741.Spro_3921; -.
DR EnsemblBacteria; ABV43016; ABV43016; Spro_3921.
DR GeneID; 64208600; -.
DR KEGG; spe:Spro_3921; -.
DR eggNOG; COG3027; Bacteria.
DR HOGENOM; CLU_116623_3_0_6; -.
DR OMA; NICYELH; -.
DR OrthoDB; 1802106at2; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.880; -; 1.
DR HAMAP; MF_02012; ZapA_type1; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR InterPro; IPR023771; Cell_div_ZapA_eubact.
DR InterPro; IPR042233; Cell_div_ZapA_N.
DR PANTHER; PTHR34981; PTHR34981; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; SSF102829; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Coiled coil; Cytoplasm; Septation.
FT CHAIN 1..109
FT /note="Cell division protein ZapA"
FT /id="PRO_0000345659"
FT COILED 71..99
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02012"
SQ SEQUENCE 109 AA; 12626 MW; 8BCCF07EB9580CC8 CRC64;
MSAQPVDIQI FGRSLRVNCP PEQQDALNMA AVDLNERLQD LKVRTRVTNT EQLVFIAALN
VCHELAQERL KTRDYASNME QRIRMLQQTI EQALLEQGRI SERQDAQFE