ZAPB_HAMD5
ID ZAPB_HAMD5 Reviewed; 79 AA.
AC C4K415;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=Cell division protein ZapB {ECO:0000255|HAMAP-Rule:MF_01196};
GN Name=zapB {ECO:0000255|HAMAP-Rule:MF_01196}; OrderedLocusNames=HDEF_0561;
OS Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; aphid secondary symbionts; Candidatus Hamiltonella.
OX NCBI_TaxID=572265;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5AT;
RX PubMed=19451630; DOI=10.1073/pnas.0900194106;
RA Degnan P.H., Yu Y., Sisneros N., Wing R.A., Moran N.A.;
RT "Hamiltonella defensa, genome evolution of protective bacterial
RT endosymbiont from pathogenic ancestors.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:9063-9068(2009).
CC -!- FUNCTION: Non-essential, abundant cell division factor that is required
CC for proper Z-ring formation. It is recruited early to the divisome by
CC direct interaction with FtsZ, stimulating Z-ring assembly and thereby
CC promoting cell division earlier in the cell cycle. Its recruitment to
CC the Z-ring requires functional FtsA or ZipA. {ECO:0000255|HAMAP-
CC Rule:MF_01196}.
CC -!- SUBUNIT: Homodimer. The ends of the coiled-coil dimer bind to each
CC other, forming polymers. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_01196}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01196}.
CC Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
CC {ECO:0000255|HAMAP-Rule:MF_01196}.
CC -!- SIMILARITY: Belongs to the ZapB family. {ECO:0000255|HAMAP-
CC Rule:MF_01196}.
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DR EMBL; CP001277; ACQ67308.1; -; Genomic_DNA.
DR RefSeq; WP_015873132.1; NC_012751.1.
DR AlphaFoldDB; C4K415; -.
DR SMR; C4K415; -.
DR STRING; 572265.HDEF_0561; -.
DR EnsemblBacteria; ACQ67308; ACQ67308; HDEF_0561.
DR GeneID; 66260441; -.
DR KEGG; hde:HDEF_0561; -.
DR eggNOG; COG3074; Bacteria.
DR HOGENOM; CLU_171174_2_0_6; -.
DR OMA; VQSAQHG; -.
DR Proteomes; UP000002334; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01196; ZapB; 1.
DR InterPro; IPR009252; Cell_div_ZapB.
DR Pfam; PF06005; ZapB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Coiled coil; Cytoplasm; Reference proteome;
KW Septation.
FT CHAIN 1..79
FT /note="Cell division protein ZapB"
FT /id="PRO_1000213804"
FT COILED 1..78
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01196"
SQ SEQUENCE 79 AA; 9229 MW; 060C6F693E3AE7E2 CRC64;
MSLEALDQLQ EKVQKMLEAN ALLQMEIEEF KEKNIVLEEK INAISAQQKD LVDQNNELKQ
EKTVWQNRLN SLLGKMDDI